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Found 2 matching records:

Displaying record number 2463

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MAb ID	alpha-p17
HXB2 Location	Gag(17-22) DNA(838..855)	Gag Epitope Map
Author Location	p17(17-22)
Epitope	EKIRLR	Epitope Alignment
Ab Type
Neutralizing
Species (Isotype)	mouse(IgG1)
Patient
Immunogen
Keywords	assay or method development

Notes

Showing 1 of 1 note.

• alpha-p17: Cy3 cyanine dye-labeled p17 peptide was used for detection of alpha-p17 Ab in a rapid colorimetric/fluorescent sensing assay. The limit of detection of the target Ab was 73pM. The assay is suggested to be a rapid screening method for HIV infection requiring minimal equipment and reagents. Sapsford2010 (assay or method development)

References

Showing 1 of 1 reference.

Sapsford2010 Kim E. Sapsford, Juan B. Blanco-Canosa, Philip E. Dawson, and Igor L. Medintz. Detection of HIV-1 Specific Monoclonal Antibodies Using Enhancement of Dye-Labeled Antigenic Peptides. Bioconjug Chem, 21(2):393-398, 17 Feb 2010. PubMed ID: 20058910. Show all entries for this paper.

Displaying record number 9

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MAb ID	32/1.24.89
HXB2 Location	Gag(17-22) DNA(838..855)	Gag Epitope Map
Author Location	p17(17-22 IIIB)
Epitope	EKIRLR	Epitope Alignment
Ab Type
Neutralizing	L
Species (Isotype)	mouse(IgG)
Patient
Immunogen	vaccine
Keywords

Vaccine Details

Notes

Showing 1 of 1 note.

• 32/1.24.89: Inhibited infectivity of cell free virus. Papsidero1989

References

Showing 1 of 1 reference.

Papsidero1989 L. D. Papsidero, M. Sheu, and F. W. Ruscetti. Human immunodeficiency virus type 1-neutralizing monoclonal antibodies which react with p17 core protein: characterization and epitope mapping. J. Virol., 63:267-272, 1989. Two Mabs with overlapping binding sites on p17 reduced the infectivity of free virus. A p24 monoclonal was not able to do this. PubMed ID: 2462060. Show all entries for this paper.