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Displaying record number 59

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Vaccine Details

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• 28 subjects were vaccinated with six HIV-1 peptides that were selected to be particularly rich in CTL epitopes, presented in lipopeptides with or without adjuvant QS21 -- HIV-specific Ab responses were detected in 25/28 (89%), proliferative in 19/28 (79%), and CTL in 13/24 (54%) of testable volunteers -- only 4/28 had Ab responses to peptide G1, 4/28 had proliferative responses, and no patient had a CTL response. Pialoux2001

References

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Pialoux2001 G. Pialoux, H. Gahery-Segard, S. Sermet, H. Poncelet, S. Fournier, L. Gerard, A. Tartar, H. Gras-Masse, J. P. Levy, J. G. Guillet, and \ANRS VAC 04 Study Team.\. Lipopeptides induce cell-mediated anti-HIV immune responses in seronegative volunteers. AIDS, 15(10):1239-49, 6 Jul 2001. PubMed ID: 11426068. Show all entries for this paper.

Displaying record number 60

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Vaccine Details

Notes

Showing 1 of 1 note.

• 28 subjects were vaccinated with six HIV-1 peptides that were selected to be particularly rich in CTL epitopes, presented in lipopeptides with or without adjuvant QS21 -- HIV-specific Ab responses were detected in 25/28 (89%), proliferative in 19/28 (79%), and CTL in 13/24 (54%) of testable volunteers -- 25/28 had Ab responses to peptide G2, 14/28 had proliferative responses, and CTL responses were detected. Pialoux2001

References

Showing 1 of 1 reference.

Pialoux2001 G. Pialoux, H. Gahery-Segard, S. Sermet, H. Poncelet, S. Fournier, L. Gerard, A. Tartar, H. Gras-Masse, J. P. Levy, J. G. Guillet, and \ANRS VAC 04 Study Team.\. Lipopeptides induce cell-mediated anti-HIV immune responses in seronegative volunteers. AIDS, 15(10):1239-49, 6 Jul 2001. PubMed ID: 11426068. Show all entries for this paper.

Displaying record number 61

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Vaccine Details

Notes

Showing 1 of 1 note.

• 28 subjects were vaccinated with six HIV-1 peptides that were selected to be particularly rich in CTL epitopes, presented in lipopeptides with or without adjuvant QS21 -- HIV-specific Ab responses were detected in 25/28 (89%), proliferative in 19/28 (79%), and CTL in 13/24 (54%) of testable volunteers -- 14/28 had non-neutralizing Ab responses to this peptide (E), 7/24 had proliferative responses, and multiple CTL responses were detected. Pialoux2001

References

Showing 1 of 1 reference.

Pialoux2001 G. Pialoux, H. Gahery-Segard, S. Sermet, H. Poncelet, S. Fournier, L. Gerard, A. Tartar, H. Gras-Masse, J. P. Levy, J. G. Guillet, and \ANRS VAC 04 Study Team.\. Lipopeptides induce cell-mediated anti-HIV immune responses in seronegative volunteers. AIDS, 15(10):1239-49, 6 Jul 2001. PubMed ID: 11426068. Show all entries for this paper.

Displaying record number 65

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Vaccine Details

Notes

Showing 1 of 1 note.

• 28 subjects were vaccinated with six HIV-1 peptides that were selected to be particularly rich in CTL epitopes, presented in lipopeptides with or without adjuvant QS21 -- HIV-specific Ab responses were detected in 10/28, proliferative in 11/14, and CTL in 13/24 (54%) of testable volunteers -- 10/28 had Ab responses to this peptide (N1), 11/24 had proliferative responses, and CTL responses were detected. Pialoux2001

References

Showing 1 of 1 reference.

Pialoux2001 G. Pialoux, H. Gahery-Segard, S. Sermet, H. Poncelet, S. Fournier, L. Gerard, A. Tartar, H. Gras-Masse, J. P. Levy, J. G. Guillet, and \ANRS VAC 04 Study Team.\. Lipopeptides induce cell-mediated anti-HIV immune responses in seronegative volunteers. AIDS, 15(10):1239-49, 6 Jul 2001. PubMed ID: 11426068. Show all entries for this paper.

Displaying record number 66

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Vaccine Details

Notes

Showing 1 of 1 note.

• 28 subjects were vaccinated with six HIV-1 peptides that were selected to be particularly rich in CTL epitopes, presented in lipopeptides with or without adjuvant QS21 -- HIV-specific Ab responses were detected in 25/28, proliferative in 3/24, and CTL in 13/24 (54%) of testable volunteers -- 20/28 had antibody responses to this particular peptide (N2), 3/24 had proliferative responses, and CTL responses were detected. Pialoux2001

References

Showing 1 of 1 reference.

Pialoux2001 G. Pialoux, H. Gahery-Segard, S. Sermet, H. Poncelet, S. Fournier, L. Gerard, A. Tartar, H. Gras-Masse, J. P. Levy, J. G. Guillet, and \ANRS VAC 04 Study Team.\. Lipopeptides induce cell-mediated anti-HIV immune responses in seronegative volunteers. AIDS, 15(10):1239-49, 6 Jul 2001. PubMed ID: 11426068. Show all entries for this paper.