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Displaying record number 714

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MAb ID	polyclonal
HXB2 Location	Env	Env Epitope Map
Author Location	gp120
Epitope
Ab Type
Neutralizing
Species (Isotype)	human
Patient
Immunogen	vaccine
Keywords

Vaccine Details

Vaccine type	protein
Vaccine strain	B clade SF2
Vaccine component	gp120
Adjuvant	MF59

Notes

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A phase I/II trial was conducted in 52 seronegative Thais immunizing with rgp120 SF2 -- the vaccine was safe and 39/40 developed NAb responses to the autologous SF2, while 22/40 were able to cross-neutralize the heterologous strain MN. Nitayaphan2000

References

Showing 1 of 1 reference.

Nitayaphan2000 S. Nitayaphan, C. Khamboonruang, N. Sirisophana, P. Morgan, J. Chiu, A. M. Duliege, C. Chuenchitra, T. Supapongse, K. Rungruengthanakit, M. de Souza, J. R. Mascola, K. Boggio, S. Ratto-Kim, L. E. Markowitz, D. Birx, V. Suriyanon, J. G. McNeil, A. E. Brown, R. A. Michael, and AFRIMS-RIHES Vaccine Evaluation Group. A phase I/II trial of HIV SF2 gp120/MF59 vaccine in seronegative Thais. Vaccine, 18(15):1448--55, 14 Feb 2000. PubMed ID: 10618542. Show all entries for this paper.