Search Antibody Database

Found 13 matching records:

Displaying record number 79

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MAb ID	2-E-4
HXB2 Location	Gag(203-217) DNA(1396..1440)	Gag Epitope Map
Author Location	p24(203-217)
Epitope	ETINEEAAEWDRVHP	Epitope Alignment
Ab Type
Neutralizing
Species (Isotype)	mouse(IgG2a)
Patient
Immunogen	vaccine
Keywords

Vaccine Details

Vaccine strain	B clade IIIB
Vaccine component	HIV-1

Notes

Showing 2 of 2 notes.

• 2-E-4: One of nine MAbs that bind to this peptide -- cross-reactive with HIV-2 ROD. Niedrig1989
• 2-E-4: Cross reactive between HIV-1, HIV-2 and SIV by ELISA, HIV-1 and HIV-2 by WB. Niedrig1988

References

Showing 2 of 2 references.

Niedrig1988 M. Niedrig, J.-P. Rabanus, J. L. Stehr, H. R. Gelderblom, and G. Pauli. Monoclonal Antibodies Directed against Human Immunodeficiency Virus Gag Proteins with Specificity for Conserved Epitopes in HIV-1, HIV-2 and Simian Immunodeficiency Virus. J. Gen. Virol., 69:2109-2114, 1988. PubMed ID: 2457067. Show all entries for this paper.

Niedrig1989 M. Niedrig, J. Hinkula, W. Weigelt, J. L'Age-Stehr, G. Pauli, J. Rosen, and B. Wahren. Epitope mapping of monoclonal antibodies against human immunodeficiency virus type 1 structural proteins by using peptides. J. Virol., 63:3525-3528, 1989. Multiple linear MAb epitopes were described in p24 and p17. Several MAbs were able to react with HIV-2 ROD and SIV MAC in an immunoblot assay, as well as with HIV-1. PubMed ID: 2473220. Show all entries for this paper.

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Displaying record number 80

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MAb ID	2-H-4
HXB2 Location	Gag(203-217) DNA(1396..1440)	Gag Epitope Map
Author Location	p24(203-217)
Epitope	ETINEEAAEWDRVHP	Epitope Alignment
Ab Type
Neutralizing
Species (Isotype)	mouse(IgG1)
Patient
Immunogen	vaccine
Keywords

Vaccine Details

Vaccine strain	B clade IIIB
Vaccine component	HIV-1

Notes

Showing 2 of 2 notes.

• 2-H-4: One of nine MAbs that bind to this peptide -- cross-reactive with HIV-2 ROD. Niedrig1989
• 2-H-4: Cross reactive between HIV-1, HIV-2 and SIV by ELISA, HIV-1 and HIV-2 by WB. Niedrig1988

References

Showing 2 of 2 references.

Niedrig1988 M. Niedrig, J.-P. Rabanus, J. L. Stehr, H. R. Gelderblom, and G. Pauli. Monoclonal Antibodies Directed against Human Immunodeficiency Virus Gag Proteins with Specificity for Conserved Epitopes in HIV-1, HIV-2 and Simian Immunodeficiency Virus. J. Gen. Virol., 69:2109-2114, 1988. PubMed ID: 2457067. Show all entries for this paper.

Niedrig1989 M. Niedrig, J. Hinkula, W. Weigelt, J. L'Age-Stehr, G. Pauli, J. Rosen, and B. Wahren. Epitope mapping of monoclonal antibodies against human immunodeficiency virus type 1 structural proteins by using peptides. J. Virol., 63:3525-3528, 1989. Multiple linear MAb epitopes were described in p24 and p17. Several MAbs were able to react with HIV-2 ROD and SIV MAC in an immunoblot assay, as well as with HIV-1. PubMed ID: 2473220. Show all entries for this paper.

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Displaying record number 81

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MAb ID	8-D-2
HXB2 Location	Gag(203-217) DNA(1396..1440)	Gag Epitope Map
Author Location	p24(203-217)
Epitope	ETINEEAAEWDRVHP	Epitope Alignment
Ab Type
Neutralizing
Species (Isotype)	mouse(IgG2a)
Patient
Immunogen	vaccine
Keywords

Vaccine Details

Vaccine strain	B clade IIIB
Vaccine component	HIV-1

Notes

Showing 2 of 2 notes.

• 8-D-2: One of nine MAbs that bind to this peptide. Niedrig1989
• 8-D-2: HIV-1 specific. Niedrig1988

References

Showing 4 of 4 references.

Niedrig1988 M. Niedrig, J.-P. Rabanus, J. L. Stehr, H. R. Gelderblom, and G. Pauli. Monoclonal Antibodies Directed against Human Immunodeficiency Virus Gag Proteins with Specificity for Conserved Epitopes in HIV-1, HIV-2 and Simian Immunodeficiency Virus. J. Gen. Virol., 69:2109-2114, 1988. PubMed ID: 2457067. Show all entries for this paper.

Niedrig1989 M. Niedrig, J. Hinkula, W. Weigelt, J. L'Age-Stehr, G. Pauli, J. Rosen, and B. Wahren. Epitope mapping of monoclonal antibodies against human immunodeficiency virus type 1 structural proteins by using peptides. J. Virol., 63:3525-3528, 1989. Multiple linear MAb epitopes were described in p24 and p17. Several MAbs were able to react with HIV-2 ROD and SIV MAC in an immunoblot assay, as well as with HIV-1. PubMed ID: 2473220. Show all entries for this paper.

RobertHebmann1992a V. Robert-Hebmann, S. Emiliani, M. Resnicoff, F. Jean, and C. Devaux. Subtyping of human immunodeficiency virus isolates with a panel of monoclonal antibodies: identification of conserved and divergent epitopes on p17 and p25 core proteins. Mol. Immunol., 29:1175-1183, 1992. PubMed ID: 1382219. Show all entries for this paper.

RobertHebmann1992b V. Robert-Hebmann, S. Emiliani, F. Jean, M. Resnicoff, and C. Devaux. Clonal Analysis of Murine B-Cell Response to the Human Immunodeficiency Virus Type 1 (HIV-1)-gag p17 and p25 Antigens. Mol. Immunol., 29:729-738, 1992. PubMed ID: 1376412. Show all entries for this paper.

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Displaying record number 82

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MAb ID	8-H-7
HXB2 Location	Gag(203-217) DNA(1396..1440)	Gag Epitope Map
Author Location	p24(203-217)
Epitope	ETINEEAAEWDRVHP	Epitope Alignment
Ab Type
Neutralizing
Species (Isotype)	mouse(IgG3)
Patient
Immunogen	vaccine
Keywords

Vaccine Details

Vaccine strain	B clade IIIB
Vaccine component	HIV-1

Notes

Showing 1 of 1 note.

• 8-H-7: One of nine MAbs that bind to this peptide. Niedrig1989

References

Showing 4 of 4 reference.

Niedrig1988 M. Niedrig, J.-P. Rabanus, J. L. Stehr, H. R. Gelderblom, and G. Pauli. Monoclonal Antibodies Directed against Human Immunodeficiency Virus Gag Proteins with Specificity for Conserved Epitopes in HIV-1, HIV-2 and Simian Immunodeficiency Virus. J. Gen. Virol., 69:2109-2114, 1988. PubMed ID: 2457067. Show all entries for this paper.

Niedrig1989 M. Niedrig, J. Hinkula, W. Weigelt, J. L'Age-Stehr, G. Pauli, J. Rosen, and B. Wahren. Epitope mapping of monoclonal antibodies against human immunodeficiency virus type 1 structural proteins by using peptides. J. Virol., 63:3525-3528, 1989. Multiple linear MAb epitopes were described in p24 and p17. Several MAbs were able to react with HIV-2 ROD and SIV MAC in an immunoblot assay, as well as with HIV-1. PubMed ID: 2473220. Show all entries for this paper.

RobertHebmann1992a V. Robert-Hebmann, S. Emiliani, M. Resnicoff, F. Jean, and C. Devaux. Subtyping of human immunodeficiency virus isolates with a panel of monoclonal antibodies: identification of conserved and divergent epitopes on p17 and p25 core proteins. Mol. Immunol., 29:1175-1183, 1992. PubMed ID: 1382219. Show all entries for this paper.

RobertHebmann1992b V. Robert-Hebmann, S. Emiliani, F. Jean, M. Resnicoff, and C. Devaux. Clonal Analysis of Murine B-Cell Response to the Human Immunodeficiency Virus Type 1 (HIV-1)-gag p17 and p25 Antigens. Mol. Immunol., 29:729-738, 1992. PubMed ID: 1376412. Show all entries for this paper.

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Displaying record number 84

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MAb ID	10-E-7
HXB2 Location	Gag(203-217) DNA(1396..1440)	Gag Epitope Map
Author Location	p24(203-217)
Epitope	ETINEEAAEWDRVHP	Epitope Alignment
Ab Type
Neutralizing
Species (Isotype)	mouse(IgG1)
Patient
Immunogen	vaccine
Keywords

Vaccine Details

Vaccine strain	B clade IIIB
Vaccine component	HIV-1

Notes

Showing 2 of 2 notes.

• 10-E-7: One of nine MAbs that bind to this peptide -- cross-reactive with HIV-2 ROD and SIV MAC. Niedrig1989
• 10-E-7: Cross reactive between HIV-1, HIV-2 and SIV. Niedrig1988

References

Showing 2 of 2 references.

Niedrig1988 M. Niedrig, J.-P. Rabanus, J. L. Stehr, H. R. Gelderblom, and G. Pauli. Monoclonal Antibodies Directed against Human Immunodeficiency Virus Gag Proteins with Specificity for Conserved Epitopes in HIV-1, HIV-2 and Simian Immunodeficiency Virus. J. Gen. Virol., 69:2109-2114, 1988. PubMed ID: 2457067. Show all entries for this paper.

Niedrig1989 M. Niedrig, J. Hinkula, W. Weigelt, J. L'Age-Stehr, G. Pauli, J. Rosen, and B. Wahren. Epitope mapping of monoclonal antibodies against human immunodeficiency virus type 1 structural proteins by using peptides. J. Virol., 63:3525-3528, 1989. Multiple linear MAb epitopes were described in p24 and p17. Several MAbs were able to react with HIV-2 ROD and SIV MAC in an immunoblot assay, as well as with HIV-1. PubMed ID: 2473220. Show all entries for this paper.

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Displaying record number 85

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MAb ID	10-G-9
HXB2 Location	Gag(203-217) DNA(1396..1440)	Gag Epitope Map
Author Location	p24(203-217)
Epitope	ETINEEAAEWDRVHP	Epitope Alignment
Ab Type
Neutralizing
Species (Isotype)	mouse(IgG1)
Patient
Immunogen	vaccine
Keywords

Vaccine Details

Vaccine strain	B clade IIIB
Vaccine component	HIV-1

Notes

Showing 2 of 2 notes.

• 10-G-9: One of nine MAbs that bind to this peptide. Niedrig1989
• 10-G-9: HIV-1 specific. Niedrig1988

References

Showing 2 of 2 references.

Niedrig1988 M. Niedrig, J.-P. Rabanus, J. L. Stehr, H. R. Gelderblom, and G. Pauli. Monoclonal Antibodies Directed against Human Immunodeficiency Virus Gag Proteins with Specificity for Conserved Epitopes in HIV-1, HIV-2 and Simian Immunodeficiency Virus. J. Gen. Virol., 69:2109-2114, 1988. PubMed ID: 2457067. Show all entries for this paper.

Niedrig1989 M. Niedrig, J. Hinkula, W. Weigelt, J. L'Age-Stehr, G. Pauli, J. Rosen, and B. Wahren. Epitope mapping of monoclonal antibodies against human immunodeficiency virus type 1 structural proteins by using peptides. J. Virol., 63:3525-3528, 1989. Multiple linear MAb epitopes were described in p24 and p17. Several MAbs were able to react with HIV-2 ROD and SIV MAC in an immunoblot assay, as well as with HIV-1. PubMed ID: 2473220. Show all entries for this paper.

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Displaying record number 86

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MAb ID	11-C-5
HXB2 Location	Gag(203-217) DNA(1396..1440)	Gag Epitope Map
Author Location	p24(203-217)
Epitope	ETINEEAAEWDRVHP	Epitope Alignment
Ab Type
Neutralizing
Species (Isotype)	mouse(IgG1)
Patient
Immunogen	vaccine
Keywords

Vaccine Details

Vaccine strain	B clade IIIB
Vaccine component	HIV-1

Notes

Showing 2 of 2 notes.

• 11-C-5: One of nine MAbs that bind to this peptide. Niedrig1989
• 11-C-5: HIV-1 specific. Niedrig1988

References

Showing 2 of 2 references.

Niedrig1988 M. Niedrig, J.-P. Rabanus, J. L. Stehr, H. R. Gelderblom, and G. Pauli. Monoclonal Antibodies Directed against Human Immunodeficiency Virus Gag Proteins with Specificity for Conserved Epitopes in HIV-1, HIV-2 and Simian Immunodeficiency Virus. J. Gen. Virol., 69:2109-2114, 1988. PubMed ID: 2457067. Show all entries for this paper.

Niedrig1989 M. Niedrig, J. Hinkula, W. Weigelt, J. L'Age-Stehr, G. Pauli, J. Rosen, and B. Wahren. Epitope mapping of monoclonal antibodies against human immunodeficiency virus type 1 structural proteins by using peptides. J. Virol., 63:3525-3528, 1989. Multiple linear MAb epitopes were described in p24 and p17. Several MAbs were able to react with HIV-2 ROD and SIV MAC in an immunoblot assay, as well as with HIV-1. PubMed ID: 2473220. Show all entries for this paper.

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Displaying record number 88

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MAb ID	1-B-7
HXB2 Location	Gag(208-217) DNA(1411..1440)	Gag Epitope Map
Author Location	p24(208-217 BH10)
Epitope	EAAEWDRVHP	Epitope Alignment
Ab Type
Neutralizing
Species (Isotype)	mouse(IgG1)
Patient
Immunogen	vaccine
Keywords

Vaccine Details

Vaccine strain	B clade IIIB

Notes

Showing 2 of 2 notes.

• 1-B-7: Similarity level of the 1-B-7 binding site pentapeptide AAEWD to the host proteome was low, with the low-similarity 5-mer occurring in the host proteome 0 times, indicating that this peptide can be used to elicit Abs for active/passive immunotherapy with low risk of cross-reaction with the host proteome. Kanduc2008
• 1-B-7: Reacts with two overlapping peptides, region of overlap is given -- reacted with HIV-2 and SIV MAC. Niedrig1989

References

Showing 3 of 3 references.

Niedrig1988 M. Niedrig, J.-P. Rabanus, J. L. Stehr, H. R. Gelderblom, and G. Pauli. Monoclonal Antibodies Directed against Human Immunodeficiency Virus Gag Proteins with Specificity for Conserved Epitopes in HIV-1, HIV-2 and Simian Immunodeficiency Virus. J. Gen. Virol., 69:2109-2114, 1988. PubMed ID: 2457067. Show all entries for this paper.

Niedrig1989 M. Niedrig, J. Hinkula, W. Weigelt, J. L'Age-Stehr, G. Pauli, J. Rosen, and B. Wahren. Epitope mapping of monoclonal antibodies against human immunodeficiency virus type 1 structural proteins by using peptides. J. Virol., 63:3525-3528, 1989. Multiple linear MAb epitopes were described in p24 and p17. Several MAbs were able to react with HIV-2 ROD and SIV MAC in an immunoblot assay, as well as with HIV-1. PubMed ID: 2473220. Show all entries for this paper.

Kanduc2008 Darja Kanduc, Rosario Serpico, Alberta Lucchese, and Yehuda Shoenfeld. Correlating Low-Similarity Peptide Sequences and HIV B-Cell Epitopes. Autoimmun. Rev., 7(4):291-296, Feb 2008. PubMed ID: 18295732. Show all entries for this paper.

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Displaying record number 89

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MAb ID	3-B-7
HXB2 Location	Gag(208-217) DNA(1411..1440)	Gag Epitope Map
Author Location	p24(208-217 BH10)
Epitope	EAAEWDRVHP	Epitope Alignment
Ab Type
Neutralizing
Species (Isotype)	mouse(IgG1)
Patient
Immunogen	vaccine
Keywords

Vaccine Details

Vaccine strain	B clade IIIB

Notes

Showing 1 of 1 note.

• 3-B-7: Reacts with two overlapping peptides, region of overlap is given -- reacted with HIV-2. Niedrig1989

References

Showing 2 of 2 reference.

Niedrig1988 M. Niedrig, J.-P. Rabanus, J. L. Stehr, H. R. Gelderblom, and G. Pauli. Monoclonal Antibodies Directed against Human Immunodeficiency Virus Gag Proteins with Specificity for Conserved Epitopes in HIV-1, HIV-2 and Simian Immunodeficiency Virus. J. Gen. Virol., 69:2109-2114, 1988. PubMed ID: 2457067. Show all entries for this paper.

Niedrig1989 M. Niedrig, J. Hinkula, W. Weigelt, J. L'Age-Stehr, G. Pauli, J. Rosen, and B. Wahren. Epitope mapping of monoclonal antibodies against human immunodeficiency virus type 1 structural proteins by using peptides. J. Virol., 63:3525-3528, 1989. Multiple linear MAb epitopes were described in p24 and p17. Several MAbs were able to react with HIV-2 ROD and SIV MAC in an immunoblot assay, as well as with HIV-1. PubMed ID: 2473220. Show all entries for this paper.

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Displaying record number 90

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MAb ID	6-D-12
HXB2 Location	Gag(208-217) DNA(1411..1440)	Gag Epitope Map
Author Location	p24(208-217 BH10)
Epitope	EAAEWDRVHP	Epitope Alignment
Ab Type
Neutralizing
Species (Isotype)	mouse(IgG1)
Patient
Immunogen	vaccine
Keywords

Vaccine Details

Vaccine strain	B clade IIIB

Notes

Showing 1 of 1 note.

• 6-D-12: Reacts with two overlapping peptides, region of overlap is given -- reacted with HIV-2. Niedrig1989

References

Showing 2 of 2 reference.

Niedrig1988 M. Niedrig, J.-P. Rabanus, J. L. Stehr, H. R. Gelderblom, and G. Pauli. Monoclonal Antibodies Directed against Human Immunodeficiency Virus Gag Proteins with Specificity for Conserved Epitopes in HIV-1, HIV-2 and Simian Immunodeficiency Virus. J. Gen. Virol., 69:2109-2114, 1988. PubMed ID: 2457067. Show all entries for this paper.

Niedrig1989 M. Niedrig, J. Hinkula, W. Weigelt, J. L'Age-Stehr, G. Pauli, J. Rosen, and B. Wahren. Epitope mapping of monoclonal antibodies against human immunodeficiency virus type 1 structural proteins by using peptides. J. Virol., 63:3525-3528, 1989. Multiple linear MAb epitopes were described in p24 and p17. Several MAbs were able to react with HIV-2 ROD and SIV MAC in an immunoblot assay, as well as with HIV-1. PubMed ID: 2473220. Show all entries for this paper.

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Displaying record number 91

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MAb ID	6-E-7
HXB2 Location	Gag(208-217) DNA(1411..1440)	Gag Epitope Map
Author Location	p24(208-217 BH10)
Epitope	EAAEWDRVHP	Epitope Alignment
Ab Type
Neutralizing
Species (Isotype)	mouse(IgG1)
Patient
Immunogen	vaccine
Keywords

Vaccine Details

Vaccine strain	B clade IIIB

Notes

Showing 1 of 1 note.

• 6-E-7: Reacts with two overlapping peptides, region of overlap is given -- reacted with HIV-2 and SIV MAC. Niedrig1989

References

Showing 2 of 2 reference.

Niedrig1988 M. Niedrig, J.-P. Rabanus, J. L. Stehr, H. R. Gelderblom, and G. Pauli. Monoclonal Antibodies Directed against Human Immunodeficiency Virus Gag Proteins with Specificity for Conserved Epitopes in HIV-1, HIV-2 and Simian Immunodeficiency Virus. J. Gen. Virol., 69:2109-2114, 1988. PubMed ID: 2457067. Show all entries for this paper.

Niedrig1989 M. Niedrig, J. Hinkula, W. Weigelt, J. L'Age-Stehr, G. Pauli, J. Rosen, and B. Wahren. Epitope mapping of monoclonal antibodies against human immunodeficiency virus type 1 structural proteins by using peptides. J. Virol., 63:3525-3528, 1989. Multiple linear MAb epitopes were described in p24 and p17. Several MAbs were able to react with HIV-2 ROD and SIV MAC in an immunoblot assay, as well as with HIV-1. PubMed ID: 2473220. Show all entries for this paper.

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Displaying record number 92

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MAb ID	8-D-5
HXB2 Location	Gag(208-217) DNA(1411..1440)	Gag Epitope Map
Author Location	p24(208-217 BH10)
Epitope	EAAEWDRVHP	Epitope Alignment
Ab Type
Neutralizing
Species (Isotype)	mouse(IgG)
Patient
Immunogen	vaccine
Keywords

Vaccine Details

Vaccine strain	B clade IIIB

Notes

Showing 1 of 1 note.

• 8-D-5: Reacts with two overlapping peptides, region of overlap is given -- bound only HIV-1. Niedrig1989

References

Showing 2 of 2 reference.

Niedrig1988 M. Niedrig, J.-P. Rabanus, J. L. Stehr, H. R. Gelderblom, and G. Pauli. Monoclonal Antibodies Directed against Human Immunodeficiency Virus Gag Proteins with Specificity for Conserved Epitopes in HIV-1, HIV-2 and Simian Immunodeficiency Virus. J. Gen. Virol., 69:2109-2114, 1988. PubMed ID: 2457067. Show all entries for this paper.

Niedrig1989 M. Niedrig, J. Hinkula, W. Weigelt, J. L'Age-Stehr, G. Pauli, J. Rosen, and B. Wahren. Epitope mapping of monoclonal antibodies against human immunodeficiency virus type 1 structural proteins by using peptides. J. Virol., 63:3525-3528, 1989. Multiple linear MAb epitopes were described in p24 and p17. Several MAbs were able to react with HIV-2 ROD and SIV MAC in an immunoblot assay, as well as with HIV-1. PubMed ID: 2473220. Show all entries for this paper.

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Displaying record number 110

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MAb ID	12-B-4
HXB2 Location	Gag(293-302) DNA(1666..1695)	Gag Epitope Map
Author Location	p24(293-302 IIIB)
Epitope	FRDYVDRFYK	Epitope Alignment
Ab Type
Neutralizing
Species (Isotype)	mouse(IgG1)
Patient
Immunogen	vaccine
Keywords

Vaccine Details

Vaccine strain	B clade IIIB
Vaccine component	HIV-1

Notes

Showing 1 of 1 note.

• 12-B-4: Epitope is defined as the overlap between two HIV-1 reactive peptides -- cross-reacts with HIV-2 ROD and SIV MAC. Niedrig1988,Niedrig1989

References

Showing 2 of 2 reference.

Niedrig1988 M. Niedrig, J.-P. Rabanus, J. L. Stehr, H. R. Gelderblom, and G. Pauli. Monoclonal Antibodies Directed against Human Immunodeficiency Virus Gag Proteins with Specificity for Conserved Epitopes in HIV-1, HIV-2 and Simian Immunodeficiency Virus. J. Gen. Virol., 69:2109-2114, 1988. PubMed ID: 2457067. Show all entries for this paper.

Niedrig1989 M. Niedrig, J. Hinkula, W. Weigelt, J. L'Age-Stehr, G. Pauli, J. Rosen, and B. Wahren. Epitope mapping of monoclonal antibodies against human immunodeficiency virus type 1 structural proteins by using peptides. J. Virol., 63:3525-3528, 1989. Multiple linear MAb epitopes were described in p24 and p17. Several MAbs were able to react with HIV-2 ROD and SIV MAC in an immunoblot assay, as well as with HIV-1. PubMed ID: 2473220. Show all entries for this paper.

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