HIV molecular immunology database

 

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Found 12 matching records:

Displaying record number 3656

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MAb ID DH511.2
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Subtype C
Ab Type gp41 MPER (membrane proximal external region)
Neutralizing P (tier 2)  View neutralization details
Contacts and Features View contacts and features
Species (Isotype) human(IgG)
Patient CH0210
Immunogen HIV-1 infection
Country South Africa
Keywords antibody binding site, antibody generation, antibody lineage, antibody sequence, broad neutralizer, computational epitope prediction, neutralization, structure, vaccine antigen design

Notes

Showing 4 of 4 notes.

References

Showing 4 of 4 references.

Isolation Paper
Williams2017 LaTonya D. Williams, Gilad Ofek, Sebastian Schätzle, Jonathan R. McDaniel, Xiaozhi Lu, Nathan I. Nicely, Liming Wu, Caleb S. Lougheed, Todd Bradley, Mark K. Louder, Krisha McKee, Robert T. Bailer, Sijy O'Dell, Ivelin S. Georgiev, Michael S. Seaman, Robert J. Parks, Dawn J. Marshall, Kara Anasti, Guang Yang, Xiaoyan Nie, Nancy L. Tumba, Kevin Wiehe, Kshitij Wagh, Bette Korber, Thomas B. Kepler, S. Munir Alam, Lynn Morris, Gift Kamanga, Myron S. Cohen, Mattia Bonsignori, Shi-Mao Xia, David C. Montefiori, Garnett Kelsoe, Feng Gao, John R. Mascola, M. Anthony Moody, Kevin O. Saunders, Hua-Xin Liao, Georgia D. Tomaras, George Georgiou, and Barton F. Haynes. Potent and Broad HIV-Neutralizing Antibodies in Memory B Cells and Plasma. Sci. Immunol., 2(7), 27 Jan 2017. PubMed ID: 28783671. Show all entries for this paper.

Haynes2016a B. F. Haynes, H. X. Liao, M. A. Moody, L. Williams, K. J. Wiehe, and G. A. Ofek. HIV-1 Neutralizing Antibodies and Uses Thereof. WIPO patent application, Sep 2016. URL: https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2016149710. Application number PCT/US2016/023488. Show all entries for this paper.

Bricault2019 Christine A. Bricault, Karina Yusim, Michael S. Seaman, Hyejin Yoon, James Theiler, Elena E. Giorgi, Kshitij Wagh, Maxwell Theiler, Peter Hraber, Jennifer P. Macke, Edward F. Kreider, Gerald H. Learn, Beatrice H. Hahn, Johannes F. Scheid, James M. Kovacs, Jennifer L. Shields, Christy L. Lavine, Fadi Ghantous, Michael Rist, Madeleine G. Bayne, George H. Neubauer, Katherine McMahan, Hanqin Peng, Coraline Chéneau, Jennifer J. Jones, Jie Zeng, Christina Ochsenbauer, Joseph P. Nkolola, Kathryn E. Stephenson, Bing Chen, S. Gnanakaran, Mattia Bonsignori, LaTonya D. Williams, Barton F. Haynes, Nicole Doria-Rose, John R. Mascola, David C. Montefiori, Dan H. Barouch, and Bette Korber. HIV-1 Neutralizing Antibody Signatures and Application to Epitope-Targeted Vaccine Design. Cell Host Microbe, 25(1):59-72.e8, 9 Jan 2019. PubMed ID: 30629920. Show all entries for this paper.

Zhang2019a Lei Zhang, Adriana Irimia, Lingling He, Elise Landais, Kimmo Rantalainen, Daniel P. Leaman, Thomas Vollbrecht, Armando Stano, Daniel I. Sands, Arthur S. Kim, IAVI Protocol G Investigators, Pascal Poignard, Dennis R. Burton, Ben Murrell, Andrew B. Ward, Jiang Zhu, Ian A. Wilson, and Michael B. Zwick. An MPER Antibody Neutralizes HIV-1 Using Germline Features Shared Among Donors. Nat. Commun., 10(1):5389, 26 Nov 2019. PubMed ID: 31772165. Show all entries for this paper.


Displaying record number 3657

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MAb ID DH511.2_K3 (DH511.2 K3, DH511 K3)
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Subtype C
Ab Type gp41 MPER (membrane proximal external region)
Neutralizing P (tier 2)  View neutralization details
Contacts and Features View contacts and features
Species (Isotype) human(IgG)
Patient CH0210
Immunogen HIV-1 infection
Country South Africa
Keywords antibody binding site, antibody generation, antibody lineage, antibody sequence, broad neutralizer, chimeric antibody, computational epitope prediction, neutralization, structure, vaccine antigen design

Notes

Showing 3 of 3 notes.

References

Showing 3 of 3 references.

Isolation Paper
Williams2017 LaTonya D. Williams, Gilad Ofek, Sebastian Schätzle, Jonathan R. McDaniel, Xiaozhi Lu, Nathan I. Nicely, Liming Wu, Caleb S. Lougheed, Todd Bradley, Mark K. Louder, Krisha McKee, Robert T. Bailer, Sijy O'Dell, Ivelin S. Georgiev, Michael S. Seaman, Robert J. Parks, Dawn J. Marshall, Kara Anasti, Guang Yang, Xiaoyan Nie, Nancy L. Tumba, Kevin Wiehe, Kshitij Wagh, Bette Korber, Thomas B. Kepler, S. Munir Alam, Lynn Morris, Gift Kamanga, Myron S. Cohen, Mattia Bonsignori, Shi-Mao Xia, David C. Montefiori, Garnett Kelsoe, Feng Gao, John R. Mascola, M. Anthony Moody, Kevin O. Saunders, Hua-Xin Liao, Georgia D. Tomaras, George Georgiou, and Barton F. Haynes. Potent and Broad HIV-Neutralizing Antibodies in Memory B Cells and Plasma. Sci. Immunol., 2(7), 27 Jan 2017. PubMed ID: 28783671. Show all entries for this paper.

Bricault2019 Christine A. Bricault, Karina Yusim, Michael S. Seaman, Hyejin Yoon, James Theiler, Elena E. Giorgi, Kshitij Wagh, Maxwell Theiler, Peter Hraber, Jennifer P. Macke, Edward F. Kreider, Gerald H. Learn, Beatrice H. Hahn, Johannes F. Scheid, James M. Kovacs, Jennifer L. Shields, Christy L. Lavine, Fadi Ghantous, Michael Rist, Madeleine G. Bayne, George H. Neubauer, Katherine McMahan, Hanqin Peng, Coraline Chéneau, Jennifer J. Jones, Jie Zeng, Christina Ochsenbauer, Joseph P. Nkolola, Kathryn E. Stephenson, Bing Chen, S. Gnanakaran, Mattia Bonsignori, LaTonya D. Williams, Barton F. Haynes, Nicole Doria-Rose, John R. Mascola, David C. Montefiori, Dan H. Barouch, and Bette Korber. HIV-1 Neutralizing Antibody Signatures and Application to Epitope-Targeted Vaccine Design. Cell Host Microbe, 25(1):59-72.e8, 9 Jan 2019. PubMed ID: 30629920. Show all entries for this paper.

Haynes2016a B. F. Haynes, H. X. Liao, M. A. Moody, L. Williams, K. J. Wiehe, and G. A. Ofek. HIV-1 Neutralizing Antibodies and Uses Thereof. WIPO patent application, Sep 2016. URL: https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2016149710. Application number PCT/US2016/023488. Show all entries for this paper.


Displaying record number 3659

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MAb ID DH512
HXB2 Location Env Env Epitope Map
Author Location gp41
Epitope
Ab Type gp41 MPER (membrane proximal external region)
Neutralizing  
Species (Isotype) human(IgG)
Patient CH0210
Immunogen HIV-1 infection
Keywords  

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Haynes2016a B. F. Haynes, H. X. Liao, M. A. Moody, L. Williams, K. J. Wiehe, and G. A. Ofek. HIV-1 Neutralizing Antibodies and Uses Thereof. WIPO patent application, Sep 2016. URL: https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2016149710. Application number PCT/US2016/023488. Show all entries for this paper.


Displaying record number 3660

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MAb ID DH512_L100dF (DH512_L100dF_4A)
HXB2 Location Env Env Epitope Map
Author Location gp41
Epitope
Ab Type gp41 MPER (membrane proximal external region)
Neutralizing  
Species (Isotype) human(IgG)
Patient CH0210
Immunogen HIV-1 infection
Keywords  

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Haynes2016a B. F. Haynes, H. X. Liao, M. A. Moody, L. Williams, K. J. Wiehe, and G. A. Ofek. HIV-1 Neutralizing Antibodies and Uses Thereof. WIPO patent application, Sep 2016. URL: https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2016149710. Application number PCT/US2016/023488. Show all entries for this paper.


Displaying record number 3661

Download this epitope record as JSON.

MAb ID DH513
HXB2 Location Env Env Epitope Map
Author Location gp41
Epitope
Ab Type gp41 MPER (membrane proximal external region)
Neutralizing  
Species (Isotype) human(IgG)
Patient CH0210
Immunogen HIV-1 infection
Keywords  

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Haynes2016a B. F. Haynes, H. X. Liao, M. A. Moody, L. Williams, K. J. Wiehe, and G. A. Ofek. HIV-1 Neutralizing Antibodies and Uses Thereof. WIPO patent application, Sep 2016. URL: https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2016149710. Application number PCT/US2016/023488. Show all entries for this paper.


Displaying record number 3662

Download this epitope record as JSON.

MAb ID DH514
HXB2 Location Env Env Epitope Map
Author Location gp41
Epitope
Ab Type gp41 MPER (membrane proximal external region)
Neutralizing  
Species (Isotype) human(IgG)
Patient CH0210
Immunogen HIV-1 infection
Keywords  

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Haynes2016a B. F. Haynes, H. X. Liao, M. A. Moody, L. Williams, K. J. Wiehe, and G. A. Ofek. HIV-1 Neutralizing Antibodies and Uses Thereof. WIPO patent application, Sep 2016. URL: https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2016149710. Application number PCT/US2016/023488. Show all entries for this paper.


Displaying record number 3663

Download this epitope record as JSON.

MAb ID DH515
HXB2 Location Env Env Epitope Map
Author Location gp41
Epitope
Ab Type gp41 MPER (membrane proximal external region)
Neutralizing  
Species (Isotype) human(IgG)
Patient CH0210
Immunogen HIV-1 infection
Keywords  

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Haynes2016a B. F. Haynes, H. X. Liao, M. A. Moody, L. Williams, K. J. Wiehe, and G. A. Ofek. HIV-1 Neutralizing Antibodies and Uses Thereof. WIPO patent application, Sep 2016. URL: https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2016149710. Application number PCT/US2016/023488. Show all entries for this paper.


Displaying record number 3664

Download this epitope record as JSON.

MAb ID DH516
HXB2 Location Env Env Epitope Map
Author Location gp41
Epitope
Ab Type gp41 MPER (membrane proximal external region)
Neutralizing  
Species (Isotype) human(IgG)
Patient CH0210
Immunogen HIV-1 infection
Keywords  

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Haynes2016a B. F. Haynes, H. X. Liao, M. A. Moody, L. Williams, K. J. Wiehe, and G. A. Ofek. HIV-1 Neutralizing Antibodies and Uses Thereof. WIPO patent application, Sep 2016. URL: https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2016149710. Application number PCT/US2016/023488. Show all entries for this paper.


Displaying record number 3665

Download this epitope record as JSON.

MAb ID DH517
HXB2 Location Env Env Epitope Map
Author Location gp41
Epitope
Ab Type gp41 MPER (membrane proximal external region)
Neutralizing P (tier 2)  View neutralization details
Species (Isotype) human(IgG)
Patient CH0210
Immunogen HIV-1 infection
Keywords antibody generation, neutralization

Notes

Showing 3 of 3 notes.

References

Showing 3 of 3 references.

Isolation Paper
Williams2017 LaTonya D. Williams, Gilad Ofek, Sebastian Schätzle, Jonathan R. McDaniel, Xiaozhi Lu, Nathan I. Nicely, Liming Wu, Caleb S. Lougheed, Todd Bradley, Mark K. Louder, Krisha McKee, Robert T. Bailer, Sijy O'Dell, Ivelin S. Georgiev, Michael S. Seaman, Robert J. Parks, Dawn J. Marshall, Kara Anasti, Guang Yang, Xiaoyan Nie, Nancy L. Tumba, Kevin Wiehe, Kshitij Wagh, Bette Korber, Thomas B. Kepler, S. Munir Alam, Lynn Morris, Gift Kamanga, Myron S. Cohen, Mattia Bonsignori, Shi-Mao Xia, David C. Montefiori, Garnett Kelsoe, Feng Gao, John R. Mascola, M. Anthony Moody, Kevin O. Saunders, Hua-Xin Liao, Georgia D. Tomaras, George Georgiou, and Barton F. Haynes. Potent and Broad HIV-Neutralizing Antibodies in Memory B Cells and Plasma. Sci. Immunol., 2(7), 27 Jan 2017. PubMed ID: 28783671. Show all entries for this paper.

Haynes2016a B. F. Haynes, H. X. Liao, M. A. Moody, L. Williams, K. J. Wiehe, and G. A. Ofek. HIV-1 Neutralizing Antibodies and Uses Thereof. WIPO patent application, Sep 2016. URL: https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2016149710. Application number PCT/US2016/023488. Show all entries for this paper.

Zhang2019a Lei Zhang, Adriana Irimia, Lingling He, Elise Landais, Kimmo Rantalainen, Daniel P. Leaman, Thomas Vollbrecht, Armando Stano, Daniel I. Sands, Arthur S. Kim, IAVI Protocol G Investigators, Pascal Poignard, Dennis R. Burton, Ben Murrell, Andrew B. Ward, Jiang Zhu, Ian A. Wilson, and Michael B. Zwick. An MPER Antibody Neutralizes HIV-1 Using Germline Features Shared Among Donors. Nat. Commun., 10(1):5389, 26 Nov 2019. PubMed ID: 31772165. Show all entries for this paper.


Displaying record number 3666

Download this epitope record as JSON.

MAb ID DH518
HXB2 Location Env Env Epitope Map
Author Location gp41
Epitope
Ab Type gp41 MPER (membrane proximal external region)
Neutralizing  
Species (Isotype) human(IgG)
Patient CH0536
Immunogen HIV-1 infection
Keywords  

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Haynes2016a B. F. Haynes, H. X. Liao, M. A. Moody, L. Williams, K. J. Wiehe, and G. A. Ofek. HIV-1 Neutralizing Antibodies and Uses Thereof. WIPO patent application, Sep 2016. URL: https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2016149710. Application number PCT/US2016/023488. Show all entries for this paper.


Displaying record number 3667

Download this epitope record as JSON.

MAb ID DH536
HXB2 Location Env Env Epitope Map
Author Location gp41
Epitope
Ab Type gp41 MPER (membrane proximal external region)
Neutralizing  
Species (Isotype) human(IgG)
Patient CH1244
Immunogen HIV-1 infection
Keywords  

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Haynes2016a B. F. Haynes, H. X. Liao, M. A. Moody, L. Williams, K. J. Wiehe, and G. A. Ofek. HIV-1 Neutralizing Antibodies and Uses Thereof. WIPO patent application, Sep 2016. URL: https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2016149710. Application number PCT/US2016/023488. Show all entries for this paper.


Displaying record number 3668

Download this epitope record as JSON.

MAb ID DH537
HXB2 Location Env Env Epitope Map
Author Location gp41
Epitope
Ab Type gp41 MPER (membrane proximal external region)
Neutralizing  
Species (Isotype) human(IgG)
Patient CH0585
Immunogen HIV-1 infection
Keywords  

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Haynes2016a B. F. Haynes, H. X. Liao, M. A. Moody, L. Williams, K. J. Wiehe, and G. A. Ofek. HIV-1 Neutralizing Antibodies and Uses Thereof. WIPO patent application, Sep 2016. URL: https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2016149710. Application number PCT/US2016/023488. Show all entries for this paper.


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