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Found 3 matching records:

Displaying record number 925

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MAb ID F1
HXB2 Location Nef(148-157)
DNA(9238..9267)
Nef Epitope Map
Author Location Nef(148-157 IIIB)
Epitope VEPDKVEEAN Epitope Alignment
VEPDKVEEAN epitope logo
Ab Type  
Neutralizing  
Species (Isotype) mouse(IgM)
Patient  
Immunogen  
Keywords  

Notes

Showing 4 of 4 notes.

References

Showing 4 of 4 references.

Fujii1993 Y. Fujii, Y. Nishino, T. Nakaya, K. Tokunaga, and K. Ikuta. Expression of Human Immunodeficiency Virus Type 1 Nef Antigen on the Surface of Acutely and Persistently Infected Human T-cells. Vaccine, 11:1240, 1993. PubMed ID: 8256505. Show all entries for this paper.

Fujii1996 Y. Fujii, K. Otake, M. Tashiro, and A. Adachi. In Vitro Cytocidal Effects of Human Immunodeficiency Virus Type 1 Nef on Unprimed Human CD4+ T Cells without MHC Restriction. J. Gen. Virol., 77:2943-2951, 1996. PubMed ID: 9000084. Show all entries for this paper.

Fujii1996b Y. Fujii, K. Otake, M. Tashiro, and A. Adachi. Human Immunodeficiency Type 1 Nef Protein on the Cell Surface Is Cytocidal for Human CD4+ T cells. FEBS Lett., 393:105-108, 1996. PubMed ID: 8804435. Show all entries for this paper.

Otake1994 K. Otake, Y. Fujii, Y. Nishino, Q. Zhong, K. Fujinaga, M. Kameoka, K. Ohki, and K. Ikuta. The Carboxyl-Terminal Region of HIV-1 Nef Protein Is a Cell Surface Domain That Can Interact with CD4+ T Cells. J. Immunol., 153:5826-5837, 1994. This study shows that the C-terminal end of Nef is accessible to Abs. This domain could bind in a soluble form to CD4+, uninfected cells, and this interaction is inhibited in the presence of the C-terminal specific antibodies. Syncytium formation was reduced by these Abs or peptides. Abs could stain IIIB/M10, but not MN/M10, infected cells, in a membrane immunofluorescence assay. PubMed ID: 7989778. Show all entries for this paper.


Displaying record number 927

Download this epitope record as JSON.

MAb ID E9
HXB2 Location Nef(158-181)
DNA(9268..9339)
Nef Epitope Map
Author Location Nef(158-206 IIIB)
Epitope KGENTSLLHPVSLHGMDDPEREVL Epitope Alignment
Ab Type  
Neutralizing  
Species (Isotype) mouse(IgM)
Patient  
Immunogen  
Keywords  

Notes

Showing 4 of 4 notes.

References

Showing 5 of 5 references.

Fujii1993 Y. Fujii, Y. Nishino, T. Nakaya, K. Tokunaga, and K. Ikuta. Expression of Human Immunodeficiency Virus Type 1 Nef Antigen on the Surface of Acutely and Persistently Infected Human T-cells. Vaccine, 11:1240, 1993. PubMed ID: 8256505. Show all entries for this paper.

Otake1994 K. Otake, Y. Fujii, Y. Nishino, Q. Zhong, K. Fujinaga, M. Kameoka, K. Ohki, and K. Ikuta. The Carboxyl-Terminal Region of HIV-1 Nef Protein Is a Cell Surface Domain That Can Interact with CD4+ T Cells. J. Immunol., 153:5826-5837, 1994. This study shows that the C-terminal end of Nef is accessible to Abs. This domain could bind in a soluble form to CD4+, uninfected cells, and this interaction is inhibited in the presence of the C-terminal specific antibodies. Syncytium formation was reduced by these Abs or peptides. Abs could stain IIIB/M10, but not MN/M10, infected cells, in a membrane immunofluorescence assay. PubMed ID: 7989778. Show all entries for this paper.

Fujii1996 Y. Fujii, K. Otake, M. Tashiro, and A. Adachi. In Vitro Cytocidal Effects of Human Immunodeficiency Virus Type 1 Nef on Unprimed Human CD4+ T Cells without MHC Restriction. J. Gen. Virol., 77:2943-2951, 1996. PubMed ID: 9000084. Show all entries for this paper.

Fujii1996b Y. Fujii, K. Otake, M. Tashiro, and A. Adachi. Human Immunodeficiency Type 1 Nef Protein on the Cell Surface Is Cytocidal for Human CD4+ T cells. FEBS Lett., 393:105-108, 1996. PubMed ID: 8804435. Show all entries for this paper.

Maksiutov2002 A. Z. Maksiutov, A. G. Bachinskii, and S. I. Bazhan. [Searching for Local Similarities Between HIV-1 and Human Proteins. Application to Vaccines]. Mol Biol (Mosk), 36(3):447-459, May-Jun 2002. Article in Russian. PubMed ID: 12068630. Show all entries for this paper.


Displaying record number 934

Download this epitope record as JSON.

MAb ID E7
HXB2 Location Nef(192-206)
DNA(9370..9414)
Nef Epitope Map
Author Location Nef(192-206 IIIB)
Epitope HHVARELHPEYFKNC Epitope Alignment
HHVARELHPEYFKNC epitope logo
Ab Type  
Neutralizing  
Species (Isotype) mouse(IgM)
Patient  
Immunogen  
Keywords  

Notes

Showing 5 of 5 notes.

References

Showing 6 of 6 references.

Fujii1993 Y. Fujii, Y. Nishino, T. Nakaya, K. Tokunaga, and K. Ikuta. Expression of Human Immunodeficiency Virus Type 1 Nef Antigen on the Surface of Acutely and Persistently Infected Human T-cells. Vaccine, 11:1240, 1993. PubMed ID: 8256505. Show all entries for this paper.

Otake1994 K. Otake, Y. Fujii, Y. Nishino, Q. Zhong, K. Fujinaga, M. Kameoka, K. Ohki, and K. Ikuta. The Carboxyl-Terminal Region of HIV-1 Nef Protein Is a Cell Surface Domain That Can Interact with CD4+ T Cells. J. Immunol., 153:5826-5837, 1994. This study shows that the C-terminal end of Nef is accessible to Abs. This domain could bind in a soluble form to CD4+, uninfected cells, and this interaction is inhibited in the presence of the C-terminal specific antibodies. Syncytium formation was reduced by these Abs or peptides. Abs could stain IIIB/M10, but not MN/M10, infected cells, in a membrane immunofluorescence assay. PubMed ID: 7989778. Show all entries for this paper.

Fujii1996 Y. Fujii, K. Otake, M. Tashiro, and A. Adachi. In Vitro Cytocidal Effects of Human Immunodeficiency Virus Type 1 Nef on Unprimed Human CD4+ T Cells without MHC Restriction. J. Gen. Virol., 77:2943-2951, 1996. PubMed ID: 9000084. Show all entries for this paper.

Fujii1996a Y. Fujii, K. Otake, Y. Fujita, N. Yamaimoto, Y. Nagai, M. Tashiro, and A. Adachi. Clustered Localization of Oligomeric Nef Protein of Human Immunodeficiency Virus Type 1 on the Cell Surface. FEBS Lett., 395:257-261, 1996. PubMed ID: 8898107. Show all entries for this paper.

Fujii1996b Y. Fujii, K. Otake, M. Tashiro, and A. Adachi. Human Immunodeficiency Type 1 Nef Protein on the Cell Surface Is Cytocidal for Human CD4+ T cells. FEBS Lett., 393:105-108, 1996. PubMed ID: 8804435. Show all entries for this paper.

Fujii1996c Y. Fujii, K. Otake, M. Tashiro, and A. Adachi. Soluble Nef Antigen of HIV-1 Is Cytotoxic for Human CD4+ T Cells. FEBS Lett., 393:93-96, 1996. PubMed ID: 8804432. Show all entries for this paper.


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