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Displaying record number 455

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MAb ID	10F10
HXB2 Location	gp160(304-320) DNA(7134..7184)	gp160 Epitope Map
Author Location	gp120( MN)
Epitope	RKRIHIGPGRAFYTT	Epitope Alignment
Ab Type	gp120 V3 // V3 glycan (V3g)
Neutralizing	L
Species (Isotype)	mouse(IgG1)
Patient
Immunogen	vaccine
Keywords

Vaccine Details

Notes

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• 2C4: Putative epitope lies within IHIGPGRAFYT -- generated by multi-epitope polypeptide immunization -- recognize MN and SC (TRSIHIGPGRAFYTT) peptides, lower affinity for SF2. Duarte1994

References

Showing 1 of 1 reference.

Duarte1994 C. A. Duarte, M. Montero, A. Seralena, R. Valdes, V. Jimenez, J. Benitez, E. Narciandi, J. Madrazo, G. Padron, G. Sanchez, G. Gilljam, K. Persson, S. Ojeda, A. Caballero, A. Miranda, M. C. Dominguez, B. Wahren, and A. Menendez. Multiepitope Polypeptide of the HIV-1 Envelope Induces Neutralizing Monoclonal Antibodies against V3 Loop. AIDS Res. Hum. Retroviruses, 10:235-243, 1994. PubMed ID: 7517147. Show all entries for this paper.

Displaying record number 456

Download this epitope record as JSON.

MAb ID	2C4
HXB2 Location	gp160(304-320) DNA(7134..7184)	gp160 Epitope Map
Author Location	gp120( MN)
Epitope	RKRIHIGPGRAFYTT	Epitope Alignment
Ab Type	gp120 V3 // V3 glycan (V3g)
Neutralizing	L (MN)
Species (Isotype)	mouse(IgG2a)
Patient
Immunogen	vaccine
Keywords

Vaccine Details

Notes

Showing 1 of 1 note.

• 2C4: Putative epitope lies within IHIGPGRAFYT -- neutralizes MN, not IIIB and SF2 -- generated by multi-epitope polypeptide immunization -- recognize MN and SC (TRSIHIGPGRAFYTT) peptides, lower affinity for SF2. Duarte1994

References

Showing 1 of 1 reference.

Duarte1994 C. A. Duarte, M. Montero, A. Seralena, R. Valdes, V. Jimenez, J. Benitez, E. Narciandi, J. Madrazo, G. Padron, G. Sanchez, G. Gilljam, K. Persson, S. Ojeda, A. Caballero, A. Miranda, M. C. Dominguez, B. Wahren, and A. Menendez. Multiepitope Polypeptide of the HIV-1 Envelope Induces Neutralizing Monoclonal Antibodies against V3 Loop. AIDS Res. Hum. Retroviruses, 10:235-243, 1994. PubMed ID: 7517147. Show all entries for this paper.