HIV molecular immunology database

 

Search Antibody Database

Found 87 matching records:

Displaying record number 3473

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MAb ID 3BNC117/10-1074
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 CD4BS, gp120 V3 // V3 glycan (V3g)
Neutralizing P (tier 2)  View neutralization details
Species (Isotype) human(IgG1)
Patient Donor 17, Patient 3
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

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References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3474

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MAb ID 3BNC117/PGT121
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 CD4BS, gp120 V3 // V3 glycan (V3g)
Neutralizing  
Species (Isotype) human(IgG1)
Patient Donor 17, Patient 3
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3475

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MAb ID 3BNC117/PGT128
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 CD4BS, gp120 V3 // V3 glycan (V3g)
Neutralizing  
Species (Isotype) human(IgG1)
Patient Donor 36, Patient 3
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3477

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MAb ID 3BNC117/10E8
HXB2 Location Env Env Epitope Map
Author Location gp160
Epitope
Ab Type gp120 CD4BS, gp41 MPER (membrane proximal external region)
Neutralizing  
Species (Isotype) human(IgG1)
Patient Donor N152, Patient 3
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

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References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3478

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MAb ID 3BNC117/PGDM1400
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 CD4BS, gp120 V2 // V2 glycan(V2g) // V2 apex
Neutralizing  
Species (Isotype) human(IgG1)
Patient Donor 84, Patient 3
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3479

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MAb ID 3BNC117/PGT145
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 CD4BS, gp120 V2 // V2 glycan(V2g) // V2 apex
Neutralizing  
Species (Isotype) human(IgG1)
Patient Donor 84, Patient 3
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3480

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MAb ID 3BNC117/8ANC195
HXB2 Location Env Env Epitope Map
Author Location gp160
Epitope
Ab Type gp120 CD4BS, gp41-gp120 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient Patient 3
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3481

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MAb ID 3BNC117/PGT151
HXB2 Location Env Env Epitope Map
Author Location gp160
Epitope
Ab Type gp120 CD4BS, fusion peptide // near gp41-gp120 interface
Neutralizing  
Species (Isotype) human
Patient Donor 31, Patient 3
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3482

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MAb ID 3BNC117/3BC176
HXB2 Location Env Env Epitope Map
Author Location gp160
Epitope
Ab Type gp120 CD4BS, gp41-gp41 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient Patient 3
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3483

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MAb ID 3BNC117/PG16
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 CD4BS, gp120 V2 // V2 glycan(V2g) // V2 apex
Neutralizing  
Species (Isotype) human(IgG1)
Patient Donor 24, Patient 3
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

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References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3512

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MAb ID PG16/PGT121
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V2 // V2 glycan(V2g) // V2 apex, gp120 V3 // V3 glycan (V3g)
Neutralizing P (tier 2)  View neutralization details
Species (Isotype) human(IgG1)
Patient Donor 17, Donor 24
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3513

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MAb ID PG16/PGT128
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V2 // V2 glycan(V2g) // V2 apex, gp120 V3 // V3 glycan (V3g)
Neutralizing P (tier 2)  View neutralization details
Species (Isotype) human(IgG1)
Patient Donor 24, Donor 36
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3514

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MAb ID PG16/10-1074
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V2 // V2 glycan(V2g) // V2 apex, gp120 V3 // V3 glycan (V3g)
Neutralizing P (tier 2)  View neutralization details
Species (Isotype) human(IgG1)
Patient Donor 17, Donor 24
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3515

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MAb ID PGT151/10-1074
HXB2 Location Env Env Epitope Map
Author Location gp160
Epitope
Ab Type gp120 V3 // V3 glycan (V3g), fusion peptide // near gp41-gp120 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient Donor 17, Donor 31
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3516

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MAb ID 8ANC195/10-1074
HXB2 Location Env Env Epitope Map
Author Location gp160
Epitope
Ab Type gp120 V3 // V3 glycan (V3g), gp41-gp120 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient Donor 17, Patient 8
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3517

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MAb ID 8ANC195/PGT128
HXB2 Location Env Env Epitope Map
Author Location gp160
Epitope
Ab Type gp120 V3 // V3 glycan (V3g), gp41-gp120 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient Donor 36, Patient 8
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3518

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MAb ID PGT151/35O22
HXB2 Location Env Env Epitope Map
Author Location gp160
Epitope
Ab Type fusion peptide // near gp41-gp120 interface, gp41-gp120 interface
Neutralizing P (tier 2)  View neutralization details
Species (Isotype) human(IgG1)
Patient Donor 31, Donor N152
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3519

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MAb ID PG16/PGT135
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V2 // V2 glycan(V2g) // V2 apex, gp120 V3 // V3 glycan (V3g)
Neutralizing  
Species (Isotype) human(IgG1)
Patient Donor 24, Donor 39
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

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References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3521

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MAb ID 8ANC195/8ANC131
HXB2 Location Env Env Epitope Map
Author Location gp160
Epitope
Ab Type gp120 CD4BS, gp41-gp120 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient Patient 8
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

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References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3522

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MAb ID 8ANC195/PGT121
HXB2 Location Env Env Epitope Map
Author Location gp160
Epitope
Ab Type gp120 V3 // V3 glycan (V3g), gp41-gp120 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient Donor 17, Patient 8
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

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References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3524

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MAb ID 8ANC195/PGT135
HXB2 Location Env Env Epitope Map
Author Location gp160
Epitope
Ab Type gp120 V3 // V3 glycan (V3g), gp41-gp120 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient Donor 39, Patient 8
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3525

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MAb ID 8ANC195/PGT151
HXB2 Location Env Env Epitope Map
Author Location gp160
Epitope
Ab Type fusion peptide // near gp41-gp120 interface, gp41-gp120 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient Donor 31, Patient 8
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3526

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MAb ID 8ANC195/3BC176
HXB2 Location Env Env Epitope Map
Author Location gp160
Epitope
Ab Type gp41-gp120 interface, gp41-gp41 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient Patient 3, Patient 8
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

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References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3527

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MAb ID 8ANC195/10E8
HXB2 Location Env Env Epitope Map
Author Location gp160
Epitope
Ab Type gp41 MPER (membrane proximal external region), gp41-gp120 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient Donor N152, Patient 8
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3528

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MAb ID 8ANC195/PG16
HXB2 Location Env Env Epitope Map
Author Location gp160
Epitope
Ab Type gp120 V2 // V2 glycan(V2g) // V2 apex, gp41-gp120 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient Donor 24, Patient 8
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

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References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3529

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MAb ID 8ANC195/PGT145
HXB2 Location Env Env Epitope Map
Author Location gp160
Epitope
Ab Type gp120 V2 // V2 glycan(V2g) // V2 apex, gp41-gp120 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient Donor 84, Patient 8
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

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References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3530

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MAb ID 8ANC195/PGDM1400
HXB2 Location Env Env Epitope Map
Author Location gp160
Epitope
Ab Type gp120 V2 // V2 glycan(V2g) // V2 apex, gp41-gp120 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient Donor 84, Patient 8
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

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References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3532

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MAb ID 8ANC195/PGT128-IgG3C
HXB2 Location Env Env Epitope Map
Author Location gp160
Epitope
Ab Type gp120 V3 // V3 glycan (V3g), gp41-gp120 interface
Neutralizing P (tier 2)  View neutralization details
Species (Isotype) human(IgG3)
Patient Donor 36, Patient 8
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

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References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3533

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MAb ID PGT151/10-1074-IgG3C
HXB2 Location Env Env Epitope Map
Author Location gp160
Epitope
Ab Type gp120 V3 // V3 glycan (V3g), fusion peptide // near gp41-gp120 interface
Neutralizing P (tier 2)  View neutralization details
Species (Isotype) human(IgG3)
Patient Donor 17, Donor 31
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

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References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3534

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MAb ID 3BNC117/PGT135-IgG3C (3BNC117-PGT135)
HXB2 Location Env Env Epitope Map
Author Location gp160
Epitope
Ab Type gp120 CD4BS, gp120 V3 // V3 glycan (V3g)
Neutralizing    View neutralization details
Species (Isotype) human(IgG3)
Patient Donor 39, Patient 3
Immunogen virus
Keywords bispecific/trispecific, immunotherapy, neutralization

Notes

Showing 2 of 2 notes.

References

Showing 2 of 2 references.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.

Wagh2018 Kshitij Wagh, Michael S. Seaman, Marshall Zingg, Tomas Fitzsimons, Dan H. Barouch, Dennis R. Burton, Mark Connors, David D. Ho, John R. Mascola, Michel C. Nussenzweig, Jeffrey Ravetch, Rajeev Gautam, Malcolm A. Martin, David C. Montefiori, and Bette Korber. Potential of Conventional \& Bispecific Broadly Neutralizing Antibodies for Prevention of HIV-1 Subtype A, C \& D Infections. PLoS Pathog., 14(3):e1006860, Mar 2018. PubMed ID: 29505593. Show all entries for this paper.


Displaying record number 3537

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MAb ID 3BNC117/10-1074-IgG3C
HXB2 Location Env Env Epitope Map
Author Location gp160
Epitope
Ab Type gp120 CD4BS, gp120 V3 // V3 glycan (V3g)
Neutralizing P (tier 2)  View neutralization details
Species (Isotype) human(IgG3)
Patient Donor 17, Patient 3
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

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References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3538

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MAb ID 3BNC117-IgG3C-
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 CD4BS
Neutralizing    View neutralization details
Species (Isotype) human(IgG3)
Patient Patient 3
Immunogen virus
Keywords neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3539

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MAb ID 10-1074-IgG3C-
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V3 // V3 glycan (V3g)
Neutralizing P (tier 2)  View neutralization details
Species (Isotype) human(IgG3)
Patient Donor 17
Immunogen virus
Keywords neutralization

Notes

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References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3540

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MAb ID 8ANC195-IgG3C-
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp41-gp120 interface
Neutralizing P (tier 2)  View neutralization details
Species (Isotype) human(IgG3)
Patient Patient 8
Immunogen virus
Keywords neutralization

Notes

Showing 1 of 1 note.

References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3541

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MAb ID PGT128-IgG3C-
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V3 // V3 glycan (V3g)
Neutralizing P (tier 2)  View neutralization details
Species (Isotype) human(IgG3)
Patient Donor 36
Immunogen virus
Keywords neutralization

Notes

Showing 1 of 1 note.

References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3542

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MAb ID PGT151-IgG3C-
HXB2 Location Env Env Epitope Map
Author Location gp160
Epitope
Ab Type fusion peptide // near gp41-gp120 interface
Neutralizing P (tier 2)  View neutralization details
Species (Isotype) human(IgG3)
Patient Donor 31
Immunogen virus
Keywords neutralization

Notes

Showing 1 of 1 note.

References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3543

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MAb ID PGT135-IgG3C-
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V3 // V3 glycan (V3g)
Neutralizing P (tier 2)  View neutralization details
Species (Isotype) human(IgG3)
Patient Donor 39
Immunogen virus
Keywords neutralization

Notes

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References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3640

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MAb ID 8ANC131/PGT121
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 CD4BS, gp120 V3 // V3 glycan (V3g)
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3641

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MAb ID 8ANC131/10-1074
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 CD4BS, gp120 V3 // V3 glycan (V3g)
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3642

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MAb ID 8ANC131/PGT128
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 CD4BS, gp120 V3 // V3 glycan (V3g)
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

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References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3671

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MAb ID 8ANC131/PGT135
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 CD4BS, gp120 V3 // V3 glycan (V3g)
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

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References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3672

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MAb ID 8ANC131/PG16
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 CD4BS, gp120 V2 // V2 glycan(V2g) // V2 apex
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

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References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3673

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MAb ID 8ANC131/PGT145
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 CD4BS, gp120 V2 // V2 glycan(V2g) // V2 apex
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3674

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MAb ID 8ANC131/PGDM1400
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 CD4BS, gp120 V2 // V2 glycan(V2g) // V2 apex
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3675

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MAb ID 8ANC131/PGT151
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 CD4BS, fusion peptide // near gp41-gp120 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3676

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MAb ID 8ANC131/3BC176
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 CD4BS, gp41-gp41 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3677

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MAb ID CH103/8ANC195
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 CD4BS, gp41-gp120 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3678

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MAb ID CH103/10E8
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 CD4BS, gp41 MPER (membrane proximal external region)
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3679

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MAb ID 8ANC131/10E8
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 CD4BS, gp41 MPER (membrane proximal external region)
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3680

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MAb ID CH103/3BC176
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 CD4BS, gp41-gp41 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3681

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MAb ID CH103/PGT151
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 CD4BS, fusion peptide // near gp41-gp120 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen HIV-1 infection
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3682

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MAb ID CH103/PGDM1400
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 CD4BS, gp120 V2 // V2 glycan(V2g) // V2 apex
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

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References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3683

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MAb ID CH103/PG16
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 CD4BS, gp120 V2 // V2 glycan(V2g) // V2 apex
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3684

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MAb ID CH103/PGT145
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 CD4BS, gp120 V2 // V2 glycan(V2g) // V2 apex
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3685

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MAb ID CH103/PGT135
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 CD4BS, gp120 V3 // V3 glycan (V3g)
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3686

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MAb ID CH103/PGT128
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 CD4BS, gp120 V3 // V3 glycan (V3g)
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

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References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3687

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MAb ID CH103/PGT121
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 CD4BS, gp120 V3 // V3 glycan (V3g)
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

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References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3688

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MAb ID 10-1074/PGT145
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V2 // V2 glycan(V2g) // V2 apex, gp120 V3 // V3 glycan (V3g)
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3689

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MAb ID 10-1074/PGDM1400
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V2 // V2 glycan(V2g) // V2 apex, gp120 V3 // V3 glycan (V3g)
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3690

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MAb ID 10-1074/3BC176
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V3 // V3 glycan (V3g), gp41-gp41 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

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References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3691

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MAb ID 10-1074/10E8
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V3 // V3 glycan (V3g), gp41 MPER (membrane proximal external region)
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3692

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MAb ID PGT121/PGT145
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V2 // V2 glycan(V2g) // V2 apex, gp120 V3 // V3 glycan (V3g)
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3694

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MAb ID PGT121/PGDM1400
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V2 // V2 glycan(V2g) // V2 apex, gp120 V3 // V3 glycan (V3g)
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3695

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MAb ID PGT121/PGT151
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V3 // V3 glycan (V3g), fusion peptide // near gp41-gp120 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

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References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3696

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MAb ID PGT121/10E8
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V3 // V3 glycan (V3g), gp41 MPER (membrane proximal external region)
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

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References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3697

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MAb ID PGT128/10E8
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V3 // V3 glycan (V3g), gp41 MPER (membrane proximal external region)
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

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References

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Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3698

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MAb ID PGT128/3BC176
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V3 // V3 glycan (V3g), gp41-gp41 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3699

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MAb ID PGT128/PGT151
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V3 // V3 glycan (V3g), fusion peptide // near gp41-gp120 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3700

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MAb ID PGT128/PGDM1400
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V2 // V2 glycan(V2g) // V2 apex, gp120 V3 // V3 glycan (V3g)
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3701

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MAb ID PGT128/PGT145
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V2 // V2 glycan(V2g) // V2 apex, gp120 V3 // V3 glycan (V3g)
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3702

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MAb ID PGT135/PGT145
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V2 // V2 glycan(V2g) // V2 apex, gp120 V3 // V3 glycan (V3g)
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3703

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MAb ID PGT135/PGDM1400
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V2 // V2 glycan(V2g) // V2 apex, gp120 V3 // V3 glycan (V3g)
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3704

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MAb ID PGT135/PGT151
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V3 // V3 glycan (V3g), fusion peptide // near gp41-gp120 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3705

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MAb ID PGT135/3BC176
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V3 // V3 glycan (V3g), gp41-gp41 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3706

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MAb ID PGT135/10E8
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V3 // V3 glycan (V3g), gp41 MPER (membrane proximal external region)
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3707

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MAb ID PGT151/10E8
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp41 MPER (membrane proximal external region), fusion peptide // near gp41-gp120 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3708

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MAb ID PGT151/3BC176
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type fusion peptide // near gp41-gp120 interface, gp41-gp41 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3709

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MAb ID PGT151/PGDM1400
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V2 // V2 glycan(V2g) // V2 apex, fusion peptide // near gp41-gp120 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3710

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MAb ID PGT151/PGT145
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V2 // V2 glycan(V2g) // V2 apex, fusion peptide // near gp41-gp120 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3711

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MAb ID PGT151/PG16
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V2 // V2 glycan(V2g) // V2 apex, fusion peptide // near gp41-gp120 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3712

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MAb ID 3BC176/PG16
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V2 // V2 glycan(V2g) // V2 apex, gp41-gp41 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3713

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MAb ID 3BC176/PGT145
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V2 // V2 glycan(V2g) // V2 apex, gp41-gp41 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3714

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MAb ID 3BC176/PGDM1400
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp41 MPER (membrane proximal external region), gp41-gp41 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3715

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MAb ID 10E8/PGDM1400
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V2 // V2 glycan(V2g) // V2 apex, gp41 MPER (membrane proximal external region)
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3716

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MAb ID 10E8/PGT145
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V2 // V2 glycan(V2g) // V2 apex, gp41 MPER (membrane proximal external region)
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3717

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MAb ID 10E8/PG16
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp120 V2 // V2 glycan(V2g) // V2 apex, gp41 MPER (membrane proximal external region)
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


Displaying record number 3718

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MAb ID 10E8/3BC176
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Ab Type gp41 MPER (membrane proximal external region), gp41-gp41 interface
Neutralizing  
Species (Isotype) human(IgG1)
Patient  
Immunogen virus
Keywords bispecific/trispecific, neutralization

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Bournazos2016 Stylianos Bournazos, Anna Gazumyan, Michael S. Seaman, Michel C. Nussenzweig, and Jeffrey V. Ravetch. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell, 165(7):1609-1620, 16 Jun 2016. PubMed ID: 27315478. Show all entries for this paper.


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