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Displaying record number 926

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MAb ID 2F2
HXB2 Location Nef(151-170)
DNA(9247..9306)
Nef Epitope Map
Author Location Nef(151-170 BRU)
Epitope DKVEEANKGENTSLLHPVSL Epitope Alignment
DKVEEANKGENTSLLHPVSL epitope logo
Ab Type  
Neutralizing  
Species (Isotype) mouse(IgG1)
Patient  
Immunogen vaccine
Keywords  

Vaccine Details

Vaccine type protein
Vaccine component Nef

Notes

Showing 6 of 6 notes.

References

Showing 4 of 4 references.

Maksiutov2002 A. Z. Maksiutov, A. G. Bachinskii, and S. I. Bazhan. [Searching for Local Similarities Between HIV-1 and Human Proteins. Application to Vaccines]. Mol Biol (Mosk), 36(3):447-459, May-Jun 2002. Article in Russian. PubMed ID: 12068630. Show all entries for this paper.

Ovod1992 V. Ovod, A. Lagerstedt, A. Ranki, F. O. Gombert, R. Spohn, M. Tahtinen, G. Jung, and K. J. Krohn. Immunological Variation and Immunohistochemical Localization of HIV-1 Nef Demonstrated with Monoclonal Antibodies. AIDS, 6:25-34, 1992. Ten anti-Nef MAbs were generated and mapped. Nef is expressed in two isomorphic forms, and was shown to be expressed mainly in the Golgi complex and at the nuclear membrane, but occasionally x in the nucleus, particularly in MT-4 cells. PubMed ID: 1371924. Show all entries for this paper.

Ranki1995 A. Ranki, M. Nyberg, V. Ovod, M. Haltia, I. Elovaara, R. Raininko, H. Haapasalo, and K. Krohn. Abundant Expression of HIV Nef and Rev Proteins in Brain Astrocytes In Vivo Is Associated with Dementia. AIDS, 9:1001-1008, 1995. HIV Nef protein was found in the brain cells of infected individuals with clinical neurological disease. PubMed ID: 8527071. Show all entries for this paper.

Saito1994 Y. Saito, L. Sharer, L. Epstein, and et. al. Overexpression of Nef as a Marker for Restricted HIV-1 Infection of Astrocytes in Postmortem Pediatric Central Nervous Tissues. Neurology, 44:474-481, 1994. PubMed ID: 8145918. Show all entries for this paper.


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