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Displaying record number 859

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MAb ID	12H2
HXB2 Location	Env	Env Epitope Map
Author Location	gp41(530-677 HXB2)
Epitope	(Discontinuous epitope)
Subtype	B
Ab Type
Neutralizing
Species (Isotype)	mouse(IgMκ)
Patient
Immunogen	vaccine
Keywords

Vaccine Details

Vaccine type	Semliki-Forest Virus
Vaccine component	Env

Notes

Showing 1 of 1 note.

12H2: Env in a Semliki-Forest Virus (SFV) vector was used to vaccinate mice intramuscularly as naked RNA, and an Ab response was induced to Env from which 12H2 was derived -- and advantage of this method is that the protein is properly expressed. Giraud1999

References

Showing 1 of 1 reference.

Giraud1999 A. Giraud, Y. Ataman-Onal, N. Battail, N. Piga, D. Brand, B. Mandrand, and B. Verrier. Generation of Monoclonal Antibodies to Native Human Immunodeficiency Virus Type 1 Envelope Glycoprotein by Immunization of Mice with Naked RNA. J. Virol. Methods, 79:75-84, 1999. PubMed ID: 10328537. Show all entries for this paper.