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Displaying record number 840

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MAb ID	1907
HXB2 Location	gp160(728-745) DNA(8406..8459)	gp160 Epitope Map
Author Location	gp41(735-752 IIIB)
Epitope	`DRPEGIEEEGGERDRDRS`	Epitope Alignment
Ab Type
Neutralizing
Species (Isotype)	mouse
Patient
Immunogen	vaccine
Keywords

Vaccine Details

Vaccine type	poliovirus
Vaccine strain	B clade IIIB
Vaccine component	gp41

Notes

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1907: Could not neutralize HIV IIIB, RF or MN. Vella1993

References

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Vella1993 C. Vella, M. Ferguson, G. Dunn, R. Meloen, H. Langedijk, D. Evans, and P. D. Minor. Characterization and Primary Structure of a Human Immunodeficiency Virus Type 1 (HIV-1) Neutralization Domain as Presented by a Poliovirus Type 1/HIV-1 Chimera. J. Gen. Virol., 7:15-21, 1993. This study elaborated on a set of antibodies first reported in Evans et al., 1989. Not all of the neutralization results are congruent between the studies. The antibodies in this study were raised to a region including the cytoplasmic domain of gp41 inserted into a poliovirus type 1/HIV-1 chimera. PubMed ID: 7506299. Show all entries for this paper.