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Displaying record number 825

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MAb ID	88-158/022
HXB2 Location	gp160(732-747) DNA(8418..8465)	gp160 Epitope Map
Author Location	gp41(732-752 IIIB)
Epitope	`GIEEEGGERDRDRSIR`	Epitope Alignment
Ab Type
Neutralizing
Species (Isotype)	mouse(IgG2b)
Patient
Immunogen	vaccine
Keywords

Vaccine Details

Vaccine type	protein
Vaccine strain	B clade IIIB
Vaccine component	gp41

Notes

Showing 1 of 1 note.

88-158/022: Mild inhibition of in vitro activity at high MAb concentrations -- profound enhancing activity at low concentrations -- significant reactivity to virion -- domain non-immunogenic in humans. Niedrig1992a

References

Showing 1 of 1 reference.

Niedrig1992a M. Niedrig, M. Broker, G. Walter, W. Stuber, H.-P. Harthus, S. Mehdi, H. R. Gelderblom, and G. Pauli. Murine monoclonal antibodies directed against the transmembrane protein gp41 of human immunodeficiency virus type 1 enhance its infectivity. J. Gen. Virol., 73:951-954, 1992. PubMed ID: 1378882. Show all entries for this paper.