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Displaying record number 812

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MAb ID	polyclonal
HXB2 Location	gp160(662-667) DNA(8208..8225)	gp160 Epitope Map
Author Location	gp41
Epitope	`ELDKWA`	Epitope Alignment
Ab Type	C-domain
Neutralizing	L P
Species (Isotype)	rabbit
Patient
Immunogen	vaccine
Keywords

Vaccine Details

Vaccine type	peptide
Vaccine component	gp41

Notes

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Low levels of anti-ELDKWA antibodies are observed in HIV-1+ individuals, so a C-domain P2 peptide linked to a carrier was used to immunize mice and rabbits, and stimulated a high-level anti-ELDKWA response in mice and rabbits -- vaccine was C-TSLIHSLIEESQNQQEKNEQELLELDKWA linked to carrier peptide K/G [(KGGG)_7-K]. Liao2000

References

Showing 1 of 1 reference.

Liao2000 M. Liao, Y. Lu, Y. Xiao, M. P. Dierich, and Y. Chen. Induction of High Level of Specific Antibody Response to the Neutralizing Epitope ELDKWA on HIV-1 gp41 by Peptide-Vaccine. Peptides, 21:463-468, 2000. PubMed ID: 10822100. Show all entries for this paper.