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MAb ID	polyclonal
HXB2 Location	Env	Env Epitope Map
Author Location	Env
Epitope
Ab Type	gp120 core variable loops (VL)
Neutralizing
Species (Isotype)	human
Patient
Immunogen	HIV-1 infection
Keywords

Notes

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Primary isolates have great differences in susceptibility to neutralization -- the variation in V1V2 and V3-V5 was measured by HTA in a set of viruses with a range of neutralization susceptibilities, and greater variability was uncorrelated with resistance to neutralization. This polyclonal bound the region of gp120 V1-V2 and V3-V5. Gordon2000

References

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Gordon2000 C. J. Gordon and E. L. Delwart. Genetic Diversity of Primary HIV-1 Isolates and their Sensitivity to Antibody-Mediated Neutralization. Virology, 272:326-330, 2000. PubMed ID: 10873775. Show all entries for this paper.