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Displaying record number 63

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MAb ID	5B2
HXB2 Location	gp160(662-667) DNA(8208..8225)	gp160 Epitope Map
Author Location	Env(669-674 IIIB)
Epitope	`ELDKWA`	Epitope Alignment
Ab Type	C-domain
Neutralizing
Species (Isotype)	mouse(IgG)
Patient
Immunogen	vaccine
Keywords

Vaccine Details

Vaccine type	peptide keyhole limpet hemocyanin (KLH) conjugate
Vaccine strain	B clade IIIB
Vaccine component	gp41

Notes

Showing 2 of 2 notes.

5B2: Peptides GPGRAFY and ELDKWA were conjugated to keyhole limpet hemocyanin and used to raise mouse MAbs -- MAb hybridomas were generated with defined specificity -- 5B2 and 9G11 bind to the peptide and to rgp41. Tian2001
5B2: There is an RT specific Ab Szilvay1992 and a gp41 specific Ab Tian2001 both called 5B2. Tian2001

References

Showing 1 of 1 references.

Tian2001 H. Tian, Y. Xiao, M. Zhu, M. P. Dierich, and Y. H. Chen. Induction of monoclonal antibodies with predefined epitope-specificity by epitope-vaccines. Immunol. Lett., 75(2):161--2, 1 Jan 2001. PubMed ID: 11137143. Show all entries for this paper.