HIV molecular immunology database


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Displaying record number 556

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MAb ID 13H8
HXB2 Location gp160(431-440)
gp160 Epitope Map
Author Location gp120(412-453)
Epitope GKAMYAPPIS Epitope Alignment
GKAMYAPPIS epitope logo
Ab Type gp120 C4
Neutralizing L
Species (Isotype) mouse(IgG)
Immunogen vaccine
Keywords binding affinity

Vaccine Details

Vaccine type protein
Vaccine strain B clade MN


Showing 5 of 5 notes.


Showing 4 of 4 references.

Nakamura1992 G. R. Nakamura, R. Byrn, K. Rosenthal, J. P. Porter, M. R. Hobbs, L. Riddle, D. J. Eastman, D. Dowbenko, T. Gregory, B. M. Fendly, and P. W. Berman. Monoclonal Antibodies to the Extracellular Domain of HIV-1 IIIB gp160 That Neutralize Infectivity, Block Binding to CD4 React with Diverse Isolates. AIDS Res. Hum. Retroviruses, 8:1875-1885, 1992. PubMed ID: 1283308. Show all entries for this paper.

Nakamura1993 G. R. Nakamura, R. Byrn, D. M. Wilkes, J. A. Fox, M. R. Hobbs, R. Hastings, H. C. Wessling, M. A. Norcross, B. M. Fendly, and P. W. Berman. Strain Specificity and Binding Affinity Requirements of Neutralizing Monoclonal Antibodies to the C4 Domain of gp120 from Human Immunodeficiency Virus Type 1. J. Virol., 67:6179-6191, 1993. Multiple CD4 binding domain antibodies are described; only one has a linear peptide reactivity (13H8). A V3 loop binding antibody is also described (1026). PubMed ID: 7690420. Show all entries for this paper.

Jeffs1996 S. A. Jeffs, J. McKeating, S. Lewis, H. Craft, D. Biram, P. E. Stephens, and R. L. Brady. Antigenicity of truncated forms of the human immunodeficiency virus type 1 envelope glycoprotein. J. Gen. Virol., 77:1403-1410, 1996. PubMed ID: 8757980. Show all entries for this paper.

Yu2010 Bin Yu, Dora P. A. J. Fonseca, Sara M. O'Rourke, and Phillip W. Berman. Protease Cleavage Sites in HIV-1 gp120 Recognized by Antigen Processing Enzymes Are Conserved and Located at Receptor Binding Sites. J. Virol., 84(3):1513-1526, Feb 2010. PubMed ID: 19939935. Show all entries for this paper.

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