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MAb ID	F5-4
HXB2 Location	Gag(285-307) DNA(1642..1710)	Gag Epitope Map
Author Location	p24(153-174 HXB2)
Epitope	`IRQGPKEPFRDYVDRFYKTLRAE`	Epitope Alignment
Subtype	B
Ab Type
Neutralizing
Species (Isotype)	mouse
Patient
Immunogen
Keywords

Notes

Showing 1 of 1 note.

F5-4: Binds to a location in the most hydrophilic region of p24. Kusk1988,Kusk1992

References

Showing 2 of 2 reference.

Kusk1988 P. Kusk, K. Ulrich, J. Zeuthen, and G. Pallesen. Immunological Characterization and Detection of the Major Core Protein p24 of the Human Immunodeficiency Virus (HIV) Using Monoclonal Antibodies. J. Acquir. Immune Defic. Syndr., 1:326-332, 1988. PubMed ID: 2464053. Show all entries for this paper.

Kusk1992 P. Kusk, T. H. Bugge, B. O. Lindhardt, E. F. Hulgaard, and K. Holmback. Mapping of Linear B-Cell Epitopes on the Major Core Protein p24 Of human immunodeficiency virus type 1. AIDS Res. Hum. Retroviruses, 8:1789-1794, 1992. . The epitope for MAb F5-2 was found to be reactive with human sera from HIV-1 infected individuals, and reactivity to this epitope was associated with disease progression and low CD4 T-cell counts. PubMed ID: 1280956. Show all entries for this paper.