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Displaying record number 54

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MAb ID 1F6
HXB2 Location Gag(284-304)
DNA(1639..1701)
Gag Epitope Map
Author Location p24(152-172 SIVmac)
Epitope CVKQGPKEPFQSYVDRFYKSL Epitope Alignment
Ab Type  
Neutralizing  
Species (Isotype) mouse(IgG1)
Patient  
Immunogen vaccine
Keywords  

Vaccine Details

Vaccine type inactivated HIV
Vaccine strain B clade AGM TYO-7
Vaccine component HIV-1

Notes

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References

Showing 1 of 1 reference.

Otteken1992 A. Otteken, S. Nick, W. Bergter, G. Voss, A.C. Faisst, C. Stahl-Hennig, and G. Hunsmann. Identification of a gag protein epitope conserved among all four groups of primate immunodeficiency viruses by using monoclonal antibodies. J. Gen. Virol., 73:2721-2724, 1992. Anti-SIVagmTYO-7 Mabs were obtained by intraperitoneal immunization of mice. Two reacted with p17 and three with p24. The anti-p24 MAbs recognized an epitope present in SIVagmTYO-7, SIVagmTYO-5, and HIV-2/SIVmac. The anti-p17 recognized an epitope present in SIVagmTYO-7, SIVagmTYO-5, HIV-2/SIVmac, SIVagmTYO-1, HIV-1, and SIVmnd. This study shows that the matrix protein expresses at least one highly conserved epitope. PubMed ID: 1383399. Show all entries for this paper.


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