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MAb ID 112/021
HXB2 Location Gag(133-152)
DNA(1186..1245)
Gag Epitope Map
Author Location p24(134-153 IIIB)
Epitope PIVQNIQGQMVHQAISPRTL Epitope Alignment
PIVQNIQGQMVHQAISPRTL epitope logo
Ab Type  
Neutralizing  
Species (Isotype) mouse(IgG1)
Patient  
Immunogen vaccine
Keywords  

Vaccine Details

Vaccine type beta-galactosidase fusion protein
Vaccine strain B clade IIIB
Vaccine component p24 Gag

Notes

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References

Showing 1 of 1 reference.

Niedrig1991 M. Niedrig, J. Hinkula, H.-P. Harthus, M. Broker, L. Hopp, G. Pauli, and B. Wahren. Characterization of murine monoclonal antibodies directed against the core proteins of human immunodeficiency virus types 1 and 2. J. Virol., 65:4529-4533, 1991. Multiple anti-HIV p24 MAbs were generated using HIV-1 IIIB p24 or HIV-2 ROD p26 as immunogens. The epitopes for these MAbs were mapped, and the cross-reactivity between HIV-1 IIIB, HIV-2 ROD and SIV MAC antigens were compared using multiple antibody binding assays. While some of the antibodies raised were cross-reactive by some or all of the assays, (ELISA, WB, immunofluorescence, immunoprecipitation and alkaline phosphatase anti-alkaline phosphatase assay), the different assays often gave different results. Only the antibodies raised to HIV-1 IIIB p24 are included in this database. PubMed ID: 1712863. Show all entries for this paper.


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