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Displaying record number 44

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MAb ID	polyclonal
HXB2 Location	Gag	Gag Epitope Map
Author Location	p24
Epitope
Ab Type
Neutralizing
Species (Isotype)	rat
Patient
Immunogen	vaccine
Keywords

Vaccine Details

Vaccine type	gp120 depleted whole killed virus
Vaccine strain	AG recombinant HZ321
Vaccine component	virus
Adjuvant	Complete Freund's Adjuvant (CFA), CpG immunostimulatory sequence (ISS)

Notes

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Lewis rats co-immunized with HIV-1 antigen in Freund's and with immunostimulatory sequences CpG stimulated increased IFNγ expressing CD4+ and CD8+ T cells and anti-p24 antibodies relative to antigen in Freund's without CpG. Moss2000

References

Showing 1 of 1 reference.

Moss2000 R. B. Moss, J. Diveley, F. C. Jensen, E. Gouveia, J. Savary, and D. J. Carlo. HIV-Specific CD4+ and CD8+ Immune Responses Are Generated with a gp120-Depleted, Whole-Killed HIV-1 Immunogen with CpG Immunostimulatory Sequences of DNA. J. Interferon Cytokine Res., 20(12):1131-1137, Dec 2000. PubMed ID: 11152580. Show all entries for this paper.