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MAb ID
HXB2 Location	gp160(59-73)	gp160 Epitope Map
Author Location	Env(66-76)
Epitope	KAYDTEVASDA	Epitope Alignment
Ab Type
Neutralizing
Species (Isotype)	human
Patient
Immunogen	HIV-1 infection, engineered
Keywords	review, vaccine antigen design

Notes

Showing 2 of 2 notes.

• HIV Env (C1 region) epitope KAYDTEVASDA is a known Ab response-eliciting immunogen. Table I lists other such peptides too.
• Cease1990: This review is about vaccine engineering using synthetic peptides, as natural HIV infection does not elicit protective immunity that can be mimicked. Previously mapped linear B and T (helper and cytotoxic) cell epitopes/peptides are tabulated in Tables I, II and III respectively. Cease1990 (vaccine antigen design, review)

References

Showing 1 of 1 references.

Cease1990 K. B. Cease. Peptide Component Vaccine Engineering: Targeting the AIDS virus. Intern Rev Immunol, 7:85-107, 1990. PubMed ID: 1722499. Show all entries for this paper.