HIV molecular immunology database

 

Search Antibody Database

Found 1 matching record:

Displaying record number 4154

Download this epitope record as JSON.

MAb ID CAP256-VRC26.25LS (VRC26.25LS)
HXB2 Location gp160 gp160 Epitope Map
Author Location gp160
Epitope
Subtype C
Ab Type gp120 V2 // V2 glycan(V2g) // V2 apex
Neutralizing P (tier2)
Species (Isotype) human
Patient CAP256
Immunogen engineered
Keywords antibody generation, broad neutralizer, immunoprophylaxis, immunotherapy, neutralization, structure

Notes

Showing 2 of 2 notes.

References

Showing 2 of 2 references.

Isolation Paper
Julg2017a Boris Julg, Lawrence J. Tartaglia, Brandon F. Keele, Kshitij Wagh, Amarendra Pegu, Devin Sok, Peter Abbink, Stephen D. Schmidt, Keyun Wang, Xuejun Chen, M. G. Joyce, Ivelin S. Georgiev, Misook Choe, Peter D. Kwong, Nicole A. Doria-Rose, Khoa Le, Mark K. Louder, Robert T. Bailer, Penny L. Moore, Bette Korber, Michael S. Seaman, Salim S. Abdool Karim, Lynn Morris, Richard A. Koup, John R. Mascola, Dennis R. Burton, and Dan H. Barouch. Broadly neutralizing antibodies targeting the HIV-1 envelope V2 apex confer protection against a clade C SHIV challenge. Sci Transl Med, 9(406):9/406/eaal1321 doi, Sep 2017. PubMed ID: 28878010 Show all entries for this paper.

Ivleva2018 Vera B. Ivleva, Nicole A. Schneck, Deepika Gollapudi, Frank Arnold, Jonathan W. Cooper, and Q. Paula Lei. Investigation of Sequence Clipping and Structural Heterogeneity of an HIV Broadly Neutralizing Antibody by a Comprehensive LC-MS Analysis. J Am Soc Mass Spectrom, 29(7):1512-1523 doi, Jul 2018. PubMed ID: 29736600 Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health