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Displaying record number 4154

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MAb ID CAP256-VRC26.25LS (VRC26.25LS)
HXB2 Location gp160 gp160 Epitope Map
Author Location gp160
Subtype C
Ab Type gp120 V2 // V2 glycan(V2g) // V2 apex
Neutralizing P (tier2)
Species (Isotype) human
Patient CAP256
Immunogen engineered
Keywords antibody generation, broad neutralizer, immunoprophylaxis, immunotherapy, neutralization, structure


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Showing 2 of 2 references.

Isolation Paper
Julg2017a Boris Julg, Lawrence J. Tartaglia, Brandon F. Keele, Kshitij Wagh, Amarendra Pegu, Devin Sok, Peter Abbink, Stephen D. Schmidt, Keyun Wang, Xuejun Chen, M. G. Joyce, Ivelin S. Georgiev, Misook Choe, Peter D. Kwong, Nicole A. Doria-Rose, Khoa Le, Mark K. Louder, Robert T. Bailer, Penny L. Moore, Bette Korber, Michael S. Seaman, Salim S. Abdool Karim, Lynn Morris, Richard A. Koup, John R. Mascola, Dennis R. Burton, and Dan H. Barouch. Broadly neutralizing antibodies targeting the HIV-1 envelope V2 apex confer protection against a clade C SHIV challenge. Sci Transl Med, 9(406):9/406/eaal1321 doi, Sep 2017. PubMed ID: 28878010 Show all entries for this paper.

Ivleva2018 Vera B. Ivleva, Nicole A. Schneck, Deepika Gollapudi, Frank Arnold, Jonathan W. Cooper, and Q. Paula Lei. Investigation of Sequence Clipping and Structural Heterogeneity of an HIV Broadly Neutralizing Antibody by a Comprehensive LC-MS Analysis. J Am Soc Mass Spectrom, 29(7):1512-1523 doi, Jul 2018. PubMed ID: 29736600 Show all entries for this paper.

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