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MAb ID | 10E8v4-5R-100cF (10E8v4-5R+100cF 10E8v4-V5R-100cF 10E8v4-V5F-100cF) | |
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HXB2 Location | Env | Env Epitope Map |
Author Location | ||
Epitope |
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Ab Type | gp41 MPER (membrane proximal external region) | |
Neutralizing | P (tier 2) View neutralization details | |
Species (Isotype) | human | |
Patient | Donor N152 | |
Immunogen | ||
Keywords | antibody generation, autologous responses, binding affinity, broad neutralizer, effector function, HAART, ART, HIV reservoir/latency/provirus, neutralization |
Showing 3 of 3 notes.
Showing 3 of 3 references.
Isolation Paper
Kwon2018
Young D. Kwon, Gwo-Yu Chuang, Baoshan Zhang, Robert T. Bailer, Nicole A. Doria-Rose, Tatyana S. Gindin, Bob Lin, Mark K. Louder, Krisha McKee, Sijy O'Dell, Amarendra Pegu, Stephen D. Schmidt, Mangaiarkarasi Asokan, Xuejun Chen, Misook Choe, Ivelin S. Georgiev, Vivian Jin, Marie Pancera, Reda Rawi, Keyun Wang, Rajoshi Chaudhuri, Lisa A. Kueltzo, Slobodanka D. Manceva, John-Paul Todd, Diana G. Scorpio, Mikyung Kim, Ellis L. Reinherz, Kshitij Wagh, Bette M. Korber, Mark Connors, Lawrence Shapiro, John R. Mascola, and Peter D. Kwong. Surface-Matrix Screening Identifies Semi-specific Interactions that Improve Potency of a Near Pan-reactive HIV-1-Neutralizing Antibody. Cell Rep., 22(7):1798-1809, 13 Feb 2018. PubMed ID: 29444432.
Show all entries for this paper.
Ren2018 Yanqin Ren, Maria Korom, Ronald Truong, Dora Chan, Szu-Han Huang, Colin C. Kovacs, Erika Benko, Jeffrey T. Safrit, John Lee, Hermes Garbán, Richard Apps, Harris Goldstein, Rebecca M. Lynch, and R. Brad Jones. Susceptibility to Neutralization by Broadly Neutralizing Antibodies Generally Correlates with Infected Cell Binding for a Panel of Clade B HIV Reactivated from Latent Reservoirs. J. Virol., 92(23), 1 Dec 2018. PubMed ID: 30209173. Show all entries for this paper.
Wilson2021 Andrew Wilson, Leyn Shakhtour, Adam Ward, Yanqin Ren, Melina Recarey, Eva Stevenson, Maria Korom, Colin Kovacs, Erika Benko, R. Brad Jones, and Rebecca M. Lynch. Characterizing the Relationship between Neutralization Sensitivity and env Gene Diversity During ART Suppression. Front. Immunol., 12:710327, 15 Sep 2021. PubMed ID: 34603284. Show all entries for this paper.
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