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Displaying record number 3956

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MAb ID N6/PGDM1400-10E8v4 (N6-LS/PGDM1400-10E8v4)
HXB2 Location gp160 gp160 Epitope Map
Author Location  
Epitope
Ab Type gp120 CD4BS, gp120 V2 // V2 glycan(V2g) // V2 apex, gp41 MPER (membrane proximal external region)
Neutralizing View neutralization details
Species (Isotype) human
Patient Donor 84, Donor N152, Z258
Immunogen HIV-1 infection, engineered
Keywords antibody generation, binding affinity, bispecific/trispecific, neutralization

Notes

Showing 2 of 2 notes.

References

Showing 1 of 1 references.

Isolation Paper
Xu2017 Ling Xu, Amarendra Pegu, Ercole Rao, Nicole Doria-Rose, Jochen Beninga, Krisha McKee, Dana M. Lord, Ronnie R. Wei, Gejing Deng, Mark Louder, Stephen D. Schmidt, Zachary Mankoff, Lan Wu, Mangaiarkarasi Asokan, Christian Beil, Christian Lange, Wulf Dirk Leuschner, Jochen Kruip, Rebecca Sendak, Young Do Kwon, Tongqing Zhou, Xuejun Chen, Robert T. Bailer, Keyun Wang, Misook Choe, Lawrence J. Tartaglia, Dan H. Barouch, Sijy O'Dell, John-Paul Todd, Dennis R. Burton, Mario Roederer, Mark Connors, Richard A. Koup, Peter D. Kwong, Zhi-Yong Yang, John R. Mascola, and Gary J. Nabel. Trispecific Broadly Neutralizing HIV Antibodies Mediate Potent SHIV Protection in Macaques. Science, 358(6359):85-90, 6 Oct 2017. PubMed ID: 28931639. Show all entries for this paper.


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