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Displaying record number 3907

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MAb ID BiIA-SG
HXB2 Location Env Env Epitope Map
Author Location  
Epitope
Ab Type gp120 V3 // V3 glycan (V3g), non-HIV: host CD4R
Neutralizing View neutralization details
Species (Isotype)  
Patient Donor 36
Immunogen engineered
Keywords antibody generation, bispecific/trispecific, broad neutralizer, immunoprophylaxis, immunotherapy

Notes

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References

Showing 2 of 2 references.

Isolation Paper
Wu2018 Xilin Wu, Jia Guo, Mengyue Niu, Minghui An, Li Liu, Hui Wang, Xia Jin, Qi Zhang, Ka Shing Lam, Tongjin Wu, Hua Wang, Qian Wang, Yanhua Du, Jingjing Li, Lin Cheng, Hang Ying Tang, Hong Shang, Linqi Zhang, Paul Zhou, and Zhiwei Chen. Tandem bispecific neutralizing antibody eliminates HIV-1 infection in humanized mice. J Clin Invest, 128(6):2239-2251, Jun 1 2018. PubMed ID: 29461979. Show all entries for this paper.

Niu2021 Mengyue Niu, Yik Chun Wong, Hui Wang, Xin Li, Chun Yin Chan, Qi Zhang, Lijun Ling, Lin Cheng, Ruoke Wang, Yanhua Du, Lok Yan Yim, Xia Jin, Haoji Zhang, Linqi Zhang, and Zhiwei Chen. Tandem bispecific antibody prevents pathogenic SHIVSF162P3CN infection and disease progression. Cell Rep, 36(8):109611 doi, Aug 2021. PubMed ID: 34433029 Show all entries for this paper.


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