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Displaying record number 3623

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MAb ID BG18 (354BG18)
HXB2 Location Env Env Epitope Map
Author Location gp160
Subtype B
Ab Type gp120 V3 // V3 glycan (V3g)
Neutralizing P (tier 2)  View neutralization details
Contacts and Features View contacts and features
Species (Isotype) human(IgG)
Patient EB354
Immunogen HIV-1 infection
Keywords antibody binding site, antibody generation, broad neutralizer, immunotherapy, neutralization, review, structure, therapeutic vaccine


Showing 3 of 3 notes.


Showing 3 of 3 references.

Isolation Paper
Freund2017 Natalia T. Freund, Haoqing Wang, Louise Scharf, Lilian Nogueira, Joshua A. Horwitz, Yotam Bar-On, Jovana Golijanin, Stuart A. Sievers, Devin Sok, Hui Cai, Julio C. Cesar Lorenzi, Ariel Halper-Stromberg, Ildiko Toth, Alicja Piechocka-Trocha, Harry B. Gristick, Marit J. van Gils, Rogier W. Sanders, Lai-Xi Wang, Michael S. Seaman, Dennis R. Burton, Anna Gazumyan, Bruce D. Walker, Anthony P. West, Jr., Pamela J. Bjorkman, and Michel C. Nussenzweig. Coexistence of Potent HIV-1 Broadly Neutralizing Antibodies and Antibody-Sensitive Viruses in a Viremic Controller. Sci. Transl. Med., 9(373), 18 Jan 2017. PubMed ID: 28100831. Show all entries for this paper.

Barnes2018 Christopher O. Barnes, Harry B. Gristick, Natalia T. Freund, Amelia Escolano, Artem Y. Lyubimov, Harald Hartweger, Anthony P. West, Jr., Aina E. Cohen, Michel C. Nussenzweig, and Pamela J. Bjorkman. Structural Characterization of a Highly-Potent V3-Glycan Broadly Neutralizing Antibody Bound to Natively-Glycosylated HIV-1 Envelope. Nat. Commun., 9(1):1251, 28 Mar 2018. PubMed ID: 29593217. Show all entries for this paper.

Walker2018 Laura M. Walker and Dennis R. Burton. Passive Immunotherapy of Viral Infections: `Super-Antibodies' Enter the Fray. Nat. Rev. Immunol., 18(5):297-308, May 2018. PubMed ID: 29379211. Show all entries for this paper.

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