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Displaying record number 3398

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MAb ID BF520.1
HXB2 Location Env Env Epitope Map
Author Location Env
Epitope
Subtype A1
Ab Type gp120 V3 // V3 glycan (V3g)
Neutralizing P (tier 2)  View neutralization details
Species (Isotype) human
Patient BF520
Immunogen HIV-1 infection
Country Kenya
Keywords antibody generation, antibody interactions, antibody lineage, antibody polyreactivity, broad neutralizer, computational prediction, effector function, germline, neutralization, responses in children, review, structure

Notes

Showing 5 of 5 notes.

References

Showing 5 of 5 references.

Isolation Paper
Simonich2016 Cassandra A. Simonich, Katherine L. Williams, Hans P. Verkerke, James A. Williams, Ruth Nduati, Kelly K. Lee, and Julie Overbaugh. HIV-1 Neutralizing Antibodies with Limited Hypermutation from an Infant. Cell, 166(1):77-87, 30 Jun 2016. PubMed ID: 27345369. Show all entries for this paper.

Kumar2023 Sanjeev Kumar, Swarandeep Singh, Arnab Chatterjee, Prashant Bajpai, Shaifali Sharma, Sanket Katpara, Rakesh Lodha, Somnath Dutta, and Kalpana Luthra. Recognition determinants of improved HIV-1 neutralization by a heavy chain matured pediatric antibody. iScience, 26(9):107579 doi, Sep 2023. PubMed ID: 37649696 Show all entries for this paper.

Simonich2019 Cassandra A. Simonich, Laura Doepker, Duncan Ralph, James A. Williams, Amrit Dhar, Zak Yaffe, Lauren Gentles, Christopher T. Small, Brian Oliver, Vladimir Vigdorovich, Vidya Mangala Prasad, Ruth Nduati, D. Noah Sather, Kelly K. Lee, Frederick A. Matsen, IV, and Julie Overbaugh. Kappa Chain Maturation Helps Drive Rapid Development of an Infant HIV-1 Broadly Neutralizing Antibody Lineage. Nat. Commun., 10(1):2190, 16 May 2019. PubMed ID: 31097697. Show all entries for this paper.

Wiehe2018 Kevin Wiehe, Todd Bradley, R. Ryan Meyerhoff, Connor Hart, Wilton B. Williams, David Easterhoff, William J. Faison, Thomas B. Kepler, Kevin O. Saunders, S. Munir Alam, Mattia Bonsignori, and Barton F. Haynes. Functional Relevance of Improbable Antibody Mutations for HIV Broadly Neutralizing Antibody Development. Cell Host Microbe, 23(6):759-765.e6, 13 Jun 2018. PubMed ID: 29861171. Show all entries for this paper.

Richardson2019 Simone I. Richardson, and Penny L. Moore. The antibody response in HIV-1-infected donors. Curr Opin HIV AIDS, 14(4):233-239 doi, Jul 2019. PubMed ID: 31033730 Show all entries for this paper.


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