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Displaying record number 3389

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MAb ID PCDN-38A (38A, PCDN38A)
HXB2 Location Env Env Epitope Map
Author Location Env
Epitope
Subtype C
Ab Type gp120 V3 // V3 glycan (V3g)
Neutralizing P (tier 2)  View neutralization details
Contacts and Features View contacts and features
Species (Isotype) human
Patient PC76
Immunogen HIV-1 infection
Keywords antibody binding site, antibody generation, antibody lineage, antibody sequence, mutation acquisition, neutralization, structure

Notes

Showing 2 of 2 notes.

References

Showing 2 of 2 references.

Isolation Paper
MacLeod2016 Daniel T. MacLeod, Nancy M Choi, Bryan Briney, Fernando Garces, Lorena S. Ver, Elise Landais, Ben Murrell, Terri Wrin, William Kilembe, Chi-Hui Liang, Alejandra Ramos, Chaoran B Bian, Lalinda Wickramasinghe, Leopold Kong, Kemal Eren, Chung-Yi Wu, Chi-Huey Wong, IAVI Protocol C Investigators and The IAVI African HIV Research Network, Sergei L. Kosakovsky-Pond, Ian A. Wilson, Dennis R. Burton, and Pascal Poignard. Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch. Immunity, 44(5):1215-1226, 17 May 2016. PubMed ID: 27192579. Show all entries for this paper.

Longo2016 Nancy S. Longo, Matthew S. Sutton, Andrea R. Shiakolas, Javier Guenaga, Marissa C. Jarosinski, Ivelin S. Georgiev, Krisha McKee, Robert T. Bailer, Mark K. Louder, Sijy O'Dell, Mark Connors, Richard T. Wyatt, John R. Mascola, and Nicole A. Doria-Rose. Multiple Antibody Lineages in One Donor Target the Glycan-V3 Supersite of the HIV-1 Envelope Glycoprotein and Display a Preference for Quaternary Binding. J. Virol., 90(23):10574-10586, 1 Dec 2016. PubMed ID: 27654288. Show all entries for this paper.


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