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Displaying record number 3314

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MAb ID DH570
HXB2 Location Env Env Epitope Map
Author Location  
Epitope
Ab Type gp41 MPER (membrane proximal external region)
Neutralizing  
Species (Isotype) macaque
Patient  
Immunogen vaccine
Keywords antibody binding site, antibody generation, antibody interactions, antibody lineage, binding affinity, neutralization, structure, variant cross-reactivity

Vaccine Details

Vaccine type vaccinia
Vaccine strain B clade JRFL
Vaccine component gp140, gp41 MPER

Notes

Showing 2 of 2 notes.

References

Showing 2 of 2 references.

Isolation Paper
Zhang2016 Ruijun Zhang, Laurent Verkoczy, Kevin Wiehe, S. Munir Alam, Nathan I. Nicely, Sampa Santra, Todd Bradley, Charles W. Pemble, 4th, Jinsong Zhang, Feng Gao, David C. Montefiori, Hilary Bouton-Verville, Garnett Kelsoe, Kevin Larimore, Phillip D. Greenberg, Robert Parks, Andrew Foulger, Jessica N. Peel, Kan Luo, Xiaozhi Lu, Ashley M. Trama, Nathan Vandergrift, Georgia D. Tomaras, Thomas B. Kepler, M. Anthony Moody, Hua-Xin Liao, and Barton F. Haynes. Initiation of Immune Tolerance-Controlled HIV gp41 Neutralizing B Cell Lineages. Sci. Transl. Med., 8(336):336ra62, 27 Apr 2016. PubMed ID: 27122615. Show all entries for this paper.

Fu2018 Qingshan Fu, Md Munan Shaik, Yongfei Cai, Fadi Ghantous, Alessandro Piai, Hanqin Peng, Sophia Rits-Volloch, Zhijun Liu, Stephen C. Harrison, Michael S. Seaman, Bing Chen, and James J. Chou. Structure of the Membrane Proximal External Region of HIV-1 Envelope Glycoprotein. Proc. Natl. Acad. Sci. U.S.A., 115(38):E8892-E8899, 18 Sep 2018. PubMed ID: 30185554. Show all entries for this paper.


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