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Displaying record number 3273

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MAb ID	7B9N
HXB2 Location	Env	Env Epitope Map
Author Location
Epitope
Subtype	B
Ab Type	gp120
Neutralizing
Species (Isotype)	human(IgG3κ)
Patient	KTS376
Immunogen	HIV-1 infection
Country	Japan
Keywords	antibody generation, binding affinity, neutralization

Notes

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9B9N: B-cell clones derived from a long-term non-progressive patient were selected for MAbs reactive to gp120. These MAbs bound to several complementary regions of gp120 and synergistically neutralized a wide range of HIV subtypes. This could be an alternative method to induction of bNAbs. RamirezValdez2015 (antibody generation, neutralization, binding affinity)

References

Showing 1 of 1 reference.

Isolation Paper
RamirezValdez2015 Kristel Paola Ramirez Valdez, Takeo Kuwata, Yasuhiro Maruta, Kazuki Tanaka, Muntasir Alam, Kazuhisa Yoshimura, and Shuzo Matsushita. Complementary and Synergistic Activities of Anti-V3, CD4bs and CD4i Antibodies Derived from a Single Individual Can Cover a Wide Range of HIV-1 Strains. Virology, 475:187-203, 15 Jan 2015. PubMed ID: 25486586. Show all entries for this paper.