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MAb ID | 1E2 (VHH 1E2) | |
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HXB2 Location | Env | Env Epitope Map |
Author Location | ||
Epitope |
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Subtype | A, C | |
Ab Type | gp120 CD4i CoRbs (Cluster C) | |
Neutralizing | P View neutralization details | |
Species (Isotype) | llama | |
Patient | llama#9 | |
Immunogen | vaccine | |
Keywords | antibody binding site, antibody generation, binding affinity, bispecific/trispecific, neutralization |
Vaccine type | protein |
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Vaccine strain | A clade UG37, C clade 97CN54 |
Vaccine component | gp140 |
Adjuvant | Other |
Showing 2 of 2 notes.
Showing 2 of 2 references.
Isolation Paper
Strokappe2012
Nika Strokappe, Agnieszka Szynol, Marlèn Aasa-Chapman, Andrea Gorlani, Anna Forsman Quigley, David Lutje Hulsik, Lei Chen, Robin Weiss, Hans de Haard, and Theo Verrips. Llama Antibody Fragments Recognizing Various Epitopes of the CD4bs Neutralize a Broad Range of HIV-1 Subtypes A, B and C. PLoS One, 7(3):e33298, 15 Mar 2012. PubMed ID: 22438910.
Show all entries for this paper.
Strokappe2019 Nika M. Strokappe, Miriam Hock, Lucy Rutten, Laura E. McCoy, Jaap W. Back, Christophe Caillat, Matthias Haffke, Robin A. Weiss, Winfried Weissenhorn, and Theo Verrips. Super Potent Bispecific Llama VHH Antibodies Neutralize HIV via a Combination of gp41 and gp120 Epitopes. Antibodies (Basel), 8(2), 18 Jun 2019. PubMed ID: 31544844. Show all entries for this paper.
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