logo image

HIV Molecular Immunology Database

Search Antibody Database

Found 1 matching record:

Displaying record number 3253

Download this epitope record as JSON.

MAb ID 1E2 (VHH 1E2)
HXB2 Location Env Env Epitope Map
Author Location  
Epitope
Subtype A, C
Ab Type gp120 CD4i CoRbs (Cluster C)
Neutralizing View neutralization details
Species (Isotype) llama
Patient llama#9
Immunogen vaccine
Keywords antibody binding site, antibody generation, binding affinity, bispecific/trispecific, neutralization

Vaccine Details

Vaccine type protein
Vaccine strain A clade UG37, C clade 97CN54
Vaccine component gp140
Adjuvant Other

Notes

Showing 2 of 2 notes.

References

Showing 2 of 2 references.

Isolation Paper
Strokappe2012 Nika Strokappe, Agnieszka Szynol, Marlèn Aasa-Chapman, Andrea Gorlani, Anna Forsman Quigley, David Lutje Hulsik, Lei Chen, Robin Weiss, Hans de Haard, and Theo Verrips. Llama Antibody Fragments Recognizing Various Epitopes of the CD4bs Neutralize a Broad Range of HIV-1 Subtypes A, B and C. PLoS One, 7(3):e33298, 15 Mar 2012. PubMed ID: 22438910. Show all entries for this paper.

Strokappe2019 Nika M. Strokappe, Miriam Hock, Lucy Rutten, Laura E. McCoy, Jaap W. Back, Christophe Caillat, Matthias Haffke, Robin A. Weiss, Winfried Weissenhorn, and Theo Verrips. Super Potent Bispecific Llama VHH Antibodies Neutralize HIV via a Combination of gp41 and gp120 Epitopes. Antibodies (Basel), 8(2), 18 Jun 2019. PubMed ID: 31544844. Show all entries for this paper.


This is a legacy search page. It is deprecated, will receive no more updates, and will eventually be removed. Please use the new search pages.

Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy's National Nuclear Security Administration
Copyright Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services LANL logo National Institutes of Health logo