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Displaying record number 3250

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MAb ID 1B5 (VHH 1B5)
HXB2 Location Env Env Epitope Map
Author Location  
Epitope
Subtype A, C
Ab Type gp120 V2-CD4BS
Neutralizing P (tier 2)  View neutralization details
Species (Isotype) llama
Patient  
Immunogen vaccine
Keywords antibody generation, glycosylation, neutralization

Vaccine Details

Vaccine type protein
Vaccine strain A clade UG37, C clade 97CN54
Vaccine component gp140
Adjuvant Other

Notes

Showing 2 of 2 notes.

References

Showing 2 of 2 references.

Isolation Paper
Strokappe2012 Nika Strokappe, Agnieszka Szynol, Marlèn Aasa-Chapman, Andrea Gorlani, Anna Forsman Quigley, David Lutje Hulsik, Lei Chen, Robin Weiss, Hans de Haard, and Theo Verrips. Llama Antibody Fragments Recognizing Various Epitopes of the CD4bs Neutralize a Broad Range of HIV-1 Subtypes A, B and C. PLoS One, 7(3):e33298, 15 Mar 2012. PubMed ID: 22438910. Show all entries for this paper.

Balla-Jhagjhoorsingh2013 Sunita S. Balla-Jhagjhoorsingh, Davide Corti, Leo Heyndrickx, Elisabeth Willems, Katleen Vereecken, David Davis, and Guido Vanham. The N276 Glycosylation Site Is Required for HIV-1 Neutralization by the CD4 Binding Site Specific HJ16 Monoclonal Antibody. PLoS One, 8(7):e68863, 2013. PubMed ID: 23874792. Show all entries for this paper.


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