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Displaying record number 3216

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MAb ID J3 (L8CJ3,VHH J3)
HXB2 Location gp160 gp160 Epitope Map
Author Location gp140
Subtype A, C
Ab Type gp120 CD4BS
Neutralizing L P (tier 2)  View neutralization details
Species (Isotype) llama
Immunogen vaccine
Keywords antibody binding site, antibody generation, broad neutralizer, neutralization

Vaccine Details

Vaccine type recombinant protein
Vaccine strain A clade UG37, C clade 97CN54
Vaccine component gp140


Showing 3 of 3 notes.


Showing 3 of 3 references.

Isolation Paper
McCoy2012 Laura E. McCoy, Anna Forsman Quigley, Nika M. Strokappe, Bianca Bulmer-Thomas, Michael S. Seaman, Daniella Mortier, Lucy Rutten, Nikita Chander, Carolyn J. Edwards, Robin Ketteler, David Davis, Theo Verrips, and Robin A. Weiss. Potent and Broad Neutralization of HIV-1 by a Llama Antibody Elicited by Immunization. J. Exp. Med., 209(6):1091-1103, 4 Jun 2012. PubMed ID: 22641382. Show all entries for this paper.

McCoy2014 Laura E. McCoy, Elisabetta Groppelli, Christophe Blanchetot, Hans de Haard, Theo Verrips, Lucy Rutten, Robin A. Weiss, and Clare Jolly. Neutralisation of HIV-1 Cell-Cell Spread by Human and Llama Antibodies. Retrovirology, 11:83, 2014. PubMed ID: 25700025. Show all entries for this paper.

McCoy2014a Laura E. McCoy, Lucy Rutten, Dan Frampton, Ian Anderson, Luke Granger, Rachael Bashford-Rogers, Gillian Dekkers, Nika M. Strokappe, Michael S. Seaman, Willie Koh, Vanina Grippo, Alexander Kliche, Theo Verrips, Paul Kellam, Ariberto Fassati, and Robin A. Weiss. Molecular Evolution of Broadly Neutralizing Llama Antibodies to the CD4-binding site of HIV-1. PLoS Pathog., 10(12):e1004552, Dec 2014. PubMed ID: 25522326. Show all entries for this paper.

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