HIV molecular immunology database

 

Search Antibody Database

Found 1 matching record:

Displaying record number 3105

Download this epitope record as JSON.

MAb ID JM4-IgG2b
HXB2 Location Env Env Epitope Map
Author Location  
Epitope
Ab Type gp120 CD4BS, gp120 CD4i
Neutralizing P (tier 2)  View neutralization details
Species (Isotype) llama(IgG2b)
Patient  
Immunogen vaccine
Keywords antibody binding site, antibody generation, broad neutralizer, structure

Vaccine Details

Vaccine type recombinant protein
Vaccine component gp140
Adjuvant Incomplete Freund's Adjuvant (IFA)

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Acharya2013 Priyamvada Acharya, Timothy S. Luongo, Ivelin S. Georgiev, Julie Matz, Stephen D. Schmidt, Mark K. Louder, Pascal Kessler, Yongping Yang, Krisha McKee, Sijy O'Dell, Lei Chen, Daniel Baty, Patrick Chames, Loic Martin, John R. Mascola, and Peter D. Kwong. Heavy Chain-Only IgG2b Llama Antibody Effects Near-Pan HIV-1 Neutralization by Recognizing a CD4-Induced Epitope That Includes Elements of Coreceptor- and CD4-Binding Sites. J. Virol., 87(18):10173-10181, Sep 2013. PubMed ID: 23843638. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health