Search Antibody Database

Found 1 matching record:

Displaying record number 3027

Download this epitope record as JSON.

MAb ID	4487
HXB2 Location	Env	Env Epitope Map
Author Location
Epitope
Ab Type	gp120 V3 // V3 glycan (V3g)
Neutralizing	tier 1, tier 2 View neutralization details
Species (Isotype)	human(IgG1λ)
Patient
Immunogen	HIV-1 infection
Country	India
Keywords	antibody generation, neutralization

Notes

Showing 1 of 1 note.

4487: Neutralizing and binding activity of 18 anti-V3 MAbs from Cameroonian and Indian patients were compared. The Cameroonian patients had CRF02_AG (Env corresponding to clade A) and Indian patients had clade C. MAbs from Cameroonian patients were significantly more cross-neutralizing than those from India, suggesting the preference for CRF02_AG for vaccine design. This novel MAb was from India, but the subtype of the infecting virus was not determined. Andrabi2013 (antibody generation, neutralization)

References

Showing 1 of 1 reference.

Isolation Paper
Andrabi2013 Raiees Andrabi, Constance Williams, Xiao-Hong Wang, Liuzhe Li, Alok K. Choudhary, Naveet Wig, Ashutosh Biswas, Kalpana Luthra, Arthur Nadas, Michael S. Seaman, Phillipe Nyambi, Susan Zolla-Pazner, and Miroslaw K. Gorny. Cross-Neutralizing Activity of Human Anti-V3 Monoclonal Antibodies Derived from Non-B Clade HIV-1 Infected Individuals. Virology, 439(2):81-88, 10 May 2013. PubMed ID: 23466102. Show all entries for this paper.