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MAb ID	Ab3
HXB2 Location	Rev(102-116) DNA(8606..8650)	Rev Epitope Map
Author Location	Rev(102-116 BRU)
Research Contact	Tony Lowe and Jonathan Karn, MRC, Cambridge
Epitope	`ILVESPTVLESDKTE`	Epitope Alignment
Ab Type
Neutralizing
Species (Isotype)	(IgG1)
Patient
Immunogen	vaccine
Keywords

Vaccine Details

Vaccine type	protein
Vaccine component	Rev

Notes

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Ab3: This binding site is at the carboxy end of Rev -- Ab3 binding was not blocked by bound HIV RNA. Henderson1997

References

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Henderson1997 B. R. Henderson and P. Percipalle. Interactions between HIV Rev and Nuclear Import and Export Factors: The Rev Nuclear Localisation Signal Mediates Specific Binding to Human Importin-beta. J. Mol. Biol., 274:693-707, 1997. PubMed ID: 9405152. Show all entries for this paper.