HIV molecular immunology database

 

Search Antibody Database

Found 1 matching record:

Displaying record number 250

Download this epitope record as JSON.

MAb ID 1G10 (IG10F4)
HXB2 Location Rev(96-105)
DNA(8588..8617)
Rev Epitope Map
Author Location Rev(95-105)
Research Contact Anne Marie Szilvay
Epitope GVGSPQILVE Epitope Alignment
GVGSPQILVE epitope logo
Ab Type  
Neutralizing  
Species (Isotype) mouse(IgG2bκ)
Patient  
Immunogen vaccine
Keywords  

Vaccine Details

Vaccine type protein
Vaccine component Rev

Notes

Showing 4 of 4 notes.

References

Showing 3 of 3 references.

Kalland1994 K. H. Kalland, A. M Szilvay, K. A. Brokstad, W. Saetrevik, and G. Haukenes. The Human Immunodeficiency Virus Type 1 Rev Protein Shuttles between the Cytoplasm and Nuclear Compartments. Mol. Cell Biol., 14:7436-7444, 1994. Ten anti-Nef MAbs were generated and mapped. Nef is expressed in two isomorphic forms, and was shown to be expressed mainly in the Golgi complex and at the nuclear membrane, but occasionally x in the nucleus, particularly in MT-4 cells. PubMed ID: 7935458. Show all entries for this paper.

Jensen1997 T. H. Jensen, A. Jensen, A. M. Szilvay, and J. Kjems. Probing the Structure of HIV-1 Rev by Protein Footprinting of Multiple Monoclonal Antibody-Binding Sites. FEBS Lett., 414:50-54, 1997. Rev was mapped using MAb protein footprinting, which gave results that agreed well with peptide mapping, but was useful for identifying a discontinuous interaction between two regions. Footprints supported a previously proposed structure (Auer et al., Biochemistry, 33 (1994) 2988-2996) predicting that a helix-loop-helix motif in Rev brings the termini of the protein into proximity. PubMed ID: 9305730. Show all entries for this paper.

Kanduc2008 Darja Kanduc, Rosario Serpico, Alberta Lucchese, and Yehuda Shoenfeld. Correlating Low-Similarity Peptide Sequences and HIV B-Cell Epitopes. Autoimmun. Rev., 7(4):291-296, Feb 2008. PubMed ID: 18295732. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health