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Displaying record number 242

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MAb ID 4G9
HXB2 Location Rev(5-15)
DNA(5982..6014)
Rev Epitope Map
Author Location Rev(5-15)
Epitope SGDSDEELIRT? Epitope Alignment
SGDSDEELIRT? epitope logo
Ab Type  
Neutralizing  
Species (Isotype) mouse
Patient  
Immunogen vaccine
Keywords  

Vaccine Details

Vaccine type protein
Vaccine component Rev

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Jensen1997 T. H. Jensen, A. Jensen, A. M. Szilvay, and J. Kjems. Probing the Structure of HIV-1 Rev by Protein Footprinting of Multiple Monoclonal Antibody-Binding Sites. FEBS Lett., 414:50-54, 1997. Rev was mapped using MAb protein footprinting, which gave results that agreed well with peptide mapping, but was useful for identifying a discontinuous interaction between two regions. Footprints supported a previously proposed structure (Auer et al., Biochemistry, 33 (1994) 2988-2996) predicting that a helix-loop-helix motif in Rev brings the termini of the protein into proximity. PubMed ID: 9305730. Show all entries for this paper.


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