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MAb ID | Fab 177 | |
---|---|---|
HXB2 Location | Env | Env Epitope Map |
Author Location | gp41 | |
Epitope |
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Subtype | A1 | |
Ab Type | ||
Neutralizing | ||
Species (Isotype) | human(IgA1) | |
Patient | ||
Immunogen | HIV-1 exposed seronegative | |
Country | Cambodia | |
Keywords | antibody generation, genital and mucosal immunity, HIV exposed persistently seronegative (HEPS), neutralization, structure, variant cross-reactivity |
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Isolation Paper
Tudor2009
D. Tudor, M. Derrien, L. Diomede, A.-S. Drillet, M. Houimel, C. Moog, J.-M. Reynes, L. Lopalco, and M. Bomsel. HIV-1 gp41-Specific Monoclonal Mucosal IgAs Derived from Highly Exposed but IgG-Seronegative Individuals Block HIV-1 Epithelial Transcytosis and Neutralize CD4+ Cell Infection: An IgA Gene and Functional Analysis. Mucosal Immunol., 2(5):412-426, Sep 2009. PubMed ID: 19587640.
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