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Displaying record number 209

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MAb ID	6-19
HXB2 Location	Pol(977-985) DNA(5013..5039)	Pol Epitope Map
Author Location	Integrase(261-270 HXB2)
Research Contact	Yoshihiro Kitamura, Div of Mol Genetics, Nat Inst of Infectious Diseases, Musashimurayama, Japan
Epitope	`RRKAKIIRD`	Epitope Alignment
Subtype	B
Ab Type	Integrase DNA binding domain
Neutralizing
Species (Isotype)	mouse(IgG2b)
Patient
Immunogen	vaccine
Keywords

Vaccine Details

Vaccine type	chimeric maltose binding protein (MBP)
Vaccine strain	B clade IIIB
Vaccine component	Int

Notes

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6-19: Inhibits the terminal cleavage and strand transfer functions of Integrase, but not the disintegration activity. Ishikawa1999

References

Showing 1 of 1 reference.

Ishikawa1999 T. Ishikawa, N. Okui, N. Kobayashi, R. Sakuma, T. Kitamura, and Y. Kitamura. Monoclonal Antibodies against The Minimal DNA-Binding domain in the Carboxy-Terminal Region of Human Immunodeficiency Virus Type 1 Integrase. J. Virol., 73:4475-4480, 1999. PubMed ID: 10196350. Show all entries for this paper.