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Displaying record number 208

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MAb ID 4-20
HXB2 Location Pol(968-976)
DNA(4986..5012)
Pol Epitope Map
Author Location Integrase(253-261 HXB2)
Research Contact Yoshihiro Kitamura, Div of Mol Genetics, Nat Inst of Infectious Diseases, Musashimurayama, Japan
Epitope DNSDIKVVP Epitope Alignment
DNSDIKVVP epitope logo
Subtype B
Ab Type Integrase DNA binding domain
Neutralizing  
Species (Isotype) mouse(IgG1)
Patient  
Immunogen vaccine
Keywords antibody polyreactivity, binding affinity, neutralization

Vaccine Details

Vaccine type chimeric maltose binding protein (MBP)
Vaccine strain B clade IIIB
Vaccine component Int

Notes

Showing 3 of 3 notes.

References

Showing 2 of 2 references.

Ishikawa1999 T. Ishikawa, N. Okui, N. Kobayashi, R. Sakuma, T. Kitamura, and Y. Kitamura. Monoclonal Antibodies against The Minimal DNA-Binding domain in the Carboxy-Terminal Region of Human Immunodeficiency Virus Type 1 Integrase. J. Virol., 73:4475-4480, 1999. PubMed ID: 10196350. Show all entries for this paper.

Mouquet2010 Hugo Mouquet, Johannes F. Scheid, Markus J. Zoller, Michelle Krogsgaard, Rene G. Ott, Shetha Shukair, Maxim N. Artyomov, John Pietzsch, Mark Connors, Florencia Pereyra, Bruce D. Walker, David D. Ho, Patrick C. Wilson, Michael S. Seaman, Herman N. Eisen, Arup K. Chakraborty, Thomas J. Hope, Jeffrey V. Ravetch, Hedda Wardemann, and Michel C. Nussenzweig. Polyreactivity Increases the Apparent Affinity of Anti-HIV Antibodies by Heteroligation. Nature, 467(7315):591-595, 30 Sep 2010. PubMed ID: 20882016. Show all entries for this paper.


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