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Displaying record number 194

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MAb ID 3F9
HXB2 Location Pol(716-731)
DNA(4230..4277)
Pol Epitope Map
Author Location Integrase(1-16 HXB2)
Epitope FLDGIDKAQDEHEKYH Epitope Alignment
FLDGIDKAQDEHEKYH epitope logo
Subtype B
Ab Type N-term
Neutralizing  
Species (Isotype) mouse(IgG1κ)
Patient  
Immunogen vaccine
Keywords  

Vaccine Details

Vaccine type protein
Vaccine strain B clade HXB2
Vaccine component Int

Notes

Showing 2 of 2 notes.

References

Showing 1 of 1 references.

Nilsen1996 B. M. Nilsen, I. R. Haugan, K. Berg, L. Olsen, P. O. Brown, and D. E. Helland. Monoclonal Antibodies against Human Immunodeficiency Virus Type 1 Integrase: Epitope Mapping and Differential Effects of Integrase Activities In Vitro. J. Virol., 70:1580-1587, 1996. In this study, 17 anti-integrase murine Mabs were generated and epitopes were mapped by deletion mutations and peptide scanning. The ability of MAb binding to inhibit (or stimulate) end-processing, DNA joining, reintegration, and disintegration enzyme functions it in vitro was determined. PubMed ID: 8627677. Show all entries for this paper.


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