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Displaying record number 1894

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MAb ID N2
HXB2 Location Env Env Epitope Map
Author Location gp41
Epitope
Ab Type gp41 NHR (N-heptad repeat), gp41 six-helix bundle, gp41 five-helix bundle (one CHR peptide of six helix bundle is missing)
Neutralizing  
Species (Isotype) human
Patient FDA2
Immunogen HIV-1 infection
Keywords antibody generation, antibody sequence, binding affinity, neutralization

Notes

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References

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Isolation Paper
Nelson2008 Josh D. Nelson, Heather Kinkead, Florence M. Brunel, Dan Leaman, Richard Jensen, John M. Louis, Toshiaki Maruyama, Carole A. Bewley, Katherine Bowdish, G. Marius Clore, Philip E. Dawson, Shana Frederickson, Rose G. Mage, Douglas D. Richman, Dennis R. Burton, and Michael B. Zwick. Antibody Elicited against the gp41 N-Heptad Repeat (NHR) Coiled-Coil Can Neutralize HIV-1 with Modest Potency but Non-Neutralizing Antibodies Also Bind to NHR Mimetics. Virology, 377(1):170-183, 20 Jul 2008. PubMed ID: 18499210. Show all entries for this paper.


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