HIV molecular immunology database

 

Search Antibody Database

Found 1 matching record:

Displaying record number 1892

Download this epitope record as JSON.

MAb ID 13K3
HXB2 Location Env Env Epitope Map
Author Location gp41
Research Contact Michael B. Zwick, The Acripps Research Institute, La Jolla, CA, USA, zwick@scripps.edu
Epitope
Ab Type gp41 NHR (N-heptad repeat), gp41 six-helix bundle and the internal trimeric coiled-coil of N-helices, gp41 five-helix bundle (one CHR peptide of six helix bundle is missing)
Neutralizing  
Species (Isotype) rabbit
Patient  
Immunogen vaccine
Keywords antibody generation, antibody sequence, neutralization

Vaccine Details

Vaccine type peptide
Vaccine component mimotopes
Adjuvant Incomplete Freund's Adjuvant (IFA)

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Isolation Paper
Nelson2008 Josh D. Nelson, Heather Kinkead, Florence M. Brunel, Dan Leaman, Richard Jensen, John M. Louis, Toshiaki Maruyama, Carole A. Bewley, Katherine Bowdish, G. Marius Clore, Philip E. Dawson, Shana Frederickson, Rose G. Mage, Douglas D. Richman, Dennis R. Burton, and Michael B. Zwick. Antibody Elicited against the gp41 N-Heptad Repeat (NHR) Coiled-Coil Can Neutralize HIV-1 with Modest Potency but Non-Neutralizing Antibodies Also Bind to NHR Mimetics. Virology, 377(1):170-183, 20 Jul 2008. PubMed ID: 18499210. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health