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Displaying record number 1862

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MAb ID C8 (VHH C8)
HXB2 Location Env Env Epitope Map
Author Location Env
Research Contact Robin A Weiss, University Colledge London, London, UK, r.weiss@ucl.ac.uk
Epitope
Ab Type gp120 CD4BS
Neutralizing View neutralization details
Species (Isotype) llama
Patient  
Immunogen vaccine
Keywords antibody binding site, antibody generation, binding affinity, kinetics, neutralization, subtype comparisons, vaccine antigen design, variant cross-reactivity

Vaccine Details

Vaccine type protein
Vaccine strain C clade 97CN54
Vaccine component gp120

Notes

Showing 3 of 3 notes.

References

Showing 2 of 2 references.

Isolation Paper
Forsman2008 Anna Forsman, Els Beirnaert, Marlén M. I. Aasa-Chapman, Bart Hoorelbeke, Karolin Hijazi, Willie Koh, Vanessa Tack, Agnieszka Szynol, Charles Kelly, Áine McKnight, Theo Verrips, Hans de Haard, and Robin A Weiss. Llama Antibody Fragments with Cross-Subtype Human Immunodeficiency Virus Type 1 (HIV-1)-Neutralizing Properties and High Affinity for HIV-1 gp120. J. Virol., 82(24):12069-12081, Dec 2008. PubMed ID: 18842738. Show all entries for this paper.

Strokappe2012 Nika Strokappe, Agnieszka Szynol, Marlèn Aasa-Chapman, Andrea Gorlani, Anna Forsman Quigley, David Lutje Hulsik, Lei Chen, Robin Weiss, Hans de Haard, and Theo Verrips. Llama Antibody Fragments Recognizing Various Epitopes of the CD4bs Neutralize a Broad Range of HIV-1 Subtypes A, B and C. PLoS One, 7(3):e33298, 15 Mar 2012. PubMed ID: 22438910. Show all entries for this paper.


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