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Displaying record number 1843

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MAb ID Fab 3663
HXB2 Location Env Env Epitope Map
Author Location gp41
Epitope
Ab Type gp41 six-helix bundle
Neutralizing  
Species (Isotype) human
Patient  
Immunogen in vitro stimulation or selection
Keywords antibody binding site, binding affinity, kinetics, neutralization

Notes

Showing 2 of 2 notes.

References

Showing 2 of 2 references.

Gustchina2007 Elena Gustchina, John M. Louis, Son N. Lam, Carole A. Bewley, and G. Marius Clore. A Monoclonal Fab Derived from a Human Nonimmune Phage Library Reveals a New Epitope on gp41 and Neutralizes Diverse Human Immunodeficiency Virus Type 1 Strains. J. Virol., 81(23):12946-12953, Dec 2007. PubMed ID: 17898046. Show all entries for this paper.

Gustchina2008 Elena Gustchina, Carole A. Bewley, and G. Marius Clore. Sequestering of the Prehairpin Intermediate of gp41 by Peptide N36Mut(e,g) Potentiates the Human Immunodeficiency Virus Type 1 Neutralizing Activity of Monoclonal Antibodies Directed against the N-Terminal Helical Repeat of gp41. J. Virol., 82(20):10032-10041, Oct 2008. PubMed ID: 18667502. Show all entries for this paper.


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