HIV molecular immunology database

 

Search Antibody Database

Found 1 matching record:

Displaying record number 1841

Download this epitope record as JSON.

MAb ID 5A9
HXB2 Location gp160 gp160 Epitope Map
Author Location  
Epitope
Ab Type gp41 cluster II, gp41 MPER (membrane proximal external region)
Neutralizing  
Species (Isotype) mouse(IgG2aκ)
Patient  
Immunogen vaccine
Keywords antibody generation, antibody interactions, binding affinity, kinetics

Vaccine Details

Vaccine type other
Vaccine strain M group consensus
Vaccine component gp140
Adjuvant CpG immunostimulatory sequence (ISS), Ribi adjuvant (MPL+TDM) (RIBI), monophosphoryl lipid A

Notes

Showing 2 of 2 notes.

References

Showing 2 of 2 references.

Isolation Paper
Alam2008 S. Munir Alam, Richard M. Scearce, Robert J. Parks, Kelly Plonk, Steven G. Plonk, Laura L. Sutherland, Miroslaw K. Gorny, Susan Zolla-Pazner, Stacie VanLeeuwen, M. Anthony Moody, Shi-Mao Xia, David C. Montefiori, Georgia D. Tomaras, Kent J. Weinhold, Salim Abdool Karim, Charles B. Hicks, Hua-Xin Liao, James Robinson, George M. Shaw, and Barton F. Haynes. Human Immunodeficiency Virus Type 1 gp41 Antibodies That Mask Membrane Proximal Region Epitopes: Antibody Binding Kinetics, Induction, and Potential for Regulation in Acute Infection. J. Virol., 82(1):115-125, Jan 2008. PubMed ID: 17942537. Show all entries for this paper.

Shen2010a Ruizhong Shen, Ernesto R. Drelichman, Diane Bimczok, Christina Ochsenbauer, John C. Kappes, Jamie A. Cannon, Daniela Tudor, Morgane Bomsel, Lesley E. Smythies, and Phillip D. Smith. GP41-Specific Antibody Blocks Cell-Free HIV Type 1 Transcytosis through Human Rectal Mucosa and Model Colonic Epithelium. J. Immunol., 184(7):3648-3655, 1 Apr 2010. PubMed ID: 20208001. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health