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Displaying record number 18

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MAb ID 12G-D7h11
HXB2 Location Gag(86-115)
DNA(1045..1134)
Gag Epitope Map
Author Location p17(86-115)
Epitope YCVHQRIEIKDTKEALDKIEEEQNKSKKKA Epitope Alignment
Ab Type  
Neutralizing  
Species (Isotype) rat(IgG2a)
Patient  
Immunogen vaccine
Keywords  

Vaccine Details

Vaccine type HIV infected-cell lysate
Vaccine strain B clade IIIB
Vaccine component HIV-1

Notes

Showing 2 of 2 notes.

References

Showing 2 of 2 references.

Shang1991 F. Shang, H. Huang, K. Revesz, H.-C. Chen, R. Herz, and A. Pinter. Characterization of monoclonal antibodies against the human immunodeficiency virus matrix protein, p17gag: identification of epitopes exposed at the surfaces of infected cells. J. Virol., 65:4798-4804, 1991. Six MAbs with linear epitopes were mapped. These Abs could only bind to HIV-infected cells that had been permeablized with acetone. Only G11g1 and G11h3, two antibodies that did not bind to peptides, but only to intact p17, could react with live HIV-1 infected cells. These antibodies were not neutralizing. PubMed ID: 1714518. Show all entries for this paper.

Maksiutov2002 A. Z. Maksiutov, A. G. Bachinskii, and S. I. Bazhan. [Searching for Local Similarities Between HIV-1 and Human Proteins. Application to Vaccines]. Mol Biol (Mosk), 36(3):447-459, May-Jun 2002. Article in Russian. PubMed ID: 12068630. Show all entries for this paper.


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