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Displaying record number 171

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MAb ID 7C4
HXB2 Location Pol Pol Epitope Map
Author Location RT(252-335)
Epitope
Epitope Name HRSINE
Ab Type RT thumb domain
Neutralizing  
Species (Isotype) mouse(IgG2a)
Patient  
Immunogen vaccine
Keywords antibody binding site, antibody generation

Vaccine Details

Vaccine type vaccinia
Vaccine strain B clade HXB2
Vaccine component RT

Notes

Showing 3 of 3 notes.

References

Showing 3 of 3 references.

Isolation Paper
Chiba1996 J. Chiba, A. Yamaguchi, Y. Suzuki, M. Nakano, W. Zhu, H. Ohba, A. Saito, H. Shinagawa, Y. Yamakawa, T. Kobayashi, and T. Kurata. A novel neutralization epitope on the `thumb' subdomain of human immunodeficiency virus type 1 reverse transcriptase revealed by a monoclonal antibody. J. Gen. Virol., 77(12):2921--9, Dec 1996. PubMed ID: 9000082. Show all entries for this paper.

Chiba1997 J. Chiba, M. Nakano, Y. Suzuki, K. Aoyama, H. Ohba, T. Kobayashi, A. Yasuda, A. Kojima, and T. Kurata. Generation of neutralizing antibody to the reverse transcriptase of human immunodeficiency virus type 1 by immunizing of mice with an infectious vaccinia virus recombinant. J. Immunol. Methods, 207:53-60, 1997. PubMed ID: 9328586. Show all entries for this paper.

Ohba2001 H. Ohba, T. Soga, T. Tomozawa, Y. Nishikawa, A. Yasuda, A. Kojima, T. Kurata, and J. Chiba. An immunodominant neutralization epitope on the `thumb' subdomain of human immunodeficiency virus type 1 reverse transcriptase revealed by phage display antibodies. J. Gen. Virol., 82(Pt 4):813--20, Apr 2001. URL: http://vir.sgmjournals.org/cgi/content/full/82/4/813. PubMed ID: 11257186. Show all entries for this paper.


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