HIV molecular immunology database


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Displaying record number 16

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MAb ID 12H-D3b3
HXB2 Location Gag(62-78)
Gag Epitope Map
Author Location p17(62-78)
Epitope GQLQPSLQTGSEELRSL Epitope Alignment
Ab Type  
Species (Isotype) rat(IgG2a)
Immunogen vaccine

Vaccine Details

Vaccine type HIV infected-cell lysate
Vaccine strain B clade IIIB
Vaccine component HIV-1


Showing 1 of 1 note.


Showing 1 of 1 reference.

Shang1991 F. Shang, H. Huang, K. Revesz, H.-C. Chen, R. Herz, and A. Pinter. Characterization of monoclonal antibodies against the human immunodeficiency virus matrix protein, p17gag: identification of epitopes exposed at the surfaces of infected cells. J. Virol., 65:4798-4804, 1991. Six MAbs with linear epitopes were mapped. These Abs could only bind to HIV-infected cells that had been permeablized with acetone. Only G11g1 and G11h3, two antibodies that did not bind to peptides, but only to intact p17, could react with live HIV-1 infected cells. These antibodies were not neutralizing. PubMed ID: 1714518. Show all entries for this paper.

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